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ALAS1 5'-aminolevulinate synthase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698093, updated on 17-Aug-2024

Summary

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Official Symbol
ALAS1provided by VGNC
Official Full Name
5'-aminolevulinate synthase 1provided by VGNC
Primary source
VGNC:VGNC:69780
See related
Ensembl:ENSMMUG00000005596
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ALAS1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (108336793..108353981)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (90011731..90028936, complement)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene POC1 centriolar protein A Neighboring gene fructose-bisphosphate aldolase A-like Neighboring gene uncharacterized LOC114676359 Neighboring gene toll like receptor 9 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1M

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5-aminolevulinate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in erythrocyte development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemoglobin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-aminolevulinate synthase, nonspecific, mitochondrial
Names
aminolevulinate, delta-, synthase 1
XP_001090440.3
XP_014986247.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    108336793..108353981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015130761.2 → XP_014986247.2  5-aminolevulinate synthase, nonspecific, mitochondrial

    UniProtKB/TrEMBL
    A0A5S6R787, A0A8J8XJZ5, F7H7H8, G7ML36, H9FR57
    Conserved Domains (2) summary
    pfam09029
    Location:2 → 137
    Preseq_ALAS; 5-aminolevulinate synthase presequence
    cl18945
    Location:197 → 602
    Beta_elim_lyase; Beta-eliminating lyase

  2. XM_001090440.4 → XP_001090440.3  5-aminolevulinate synthase, nonspecific, mitochondrial

    UniProtKB/TrEMBL
    A0A5S6R787, A0A8J8XJZ5, F7H7H8, G7ML36, H9FR57
    Related
    ENSMMUP00000007397.3, ENSMMUT00000007871.4
    Conserved Domains (2) summary
    pfam09029
    Location:2 → 137
    Preseq_ALAS; 5-aminolevulinate synthase presequence
    cl18945
    Location:197 → 602
    Beta_elim_lyase; Beta-eliminating lyase
Nucleotide Protein
Heading Accession and Version

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