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DOCK8 dedicator of cytokinesis 8 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698081, updated on 17-Aug-2024

Summary

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Official Symbol
DOCK8provided by VGNC
Official Full Name
dedicator of cytokinesis 8provided by VGNC
Primary source
VGNC:VGNC:71865
See related
Ensembl:ENSMMUG00000016976
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DOCK8 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
52
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (83396629..83636142, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (84096566..84383020, complement)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L12 pseudogene Neighboring gene uncharacterized LOC114672806 Neighboring gene V-type proton ATPase subunit D pseudogene Neighboring gene Zn regulated GTPase metalloprotein activator 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of establishment of T cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell leading edge IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dedicator of cytokinesis protein 8
Names
dedicator of cytokinesis protein 8-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    83396629..83636142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015117845.2 → XP_014973331.2  dedicator of cytokinesis protein 8 isoform X1

    UniProtKB/TrEMBL
    G7NG93
    Related
    ENSMMUP00000079412.1, ENSMMUT00000092827.1
    Conserved Domains (3) summary
    cd08696
    Location:559 → 739
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1635 → 2056
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:73 → 164
    DUF3398; Domain of unknown function (DUF3398)

  2. XM_028835223.1 → XP_028691056.1  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    F7AZW3, F7BL55, G7NG93
    Conserved Domains (3) summary
    cd08696
    Location:491 → 671
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1567 → 1988
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:5 → 96
    DUF3398; Domain of unknown function (DUF3398)

  3. XM_015117843.2 → XP_014973329.2  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    F7AZW3, F7BL55, G7NG93
    Related
    ENSMMUP00000022330.4, ENSMMUT00000023857.4
    Conserved Domains (3) summary
    cd08696
    Location:491 → 671
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1567 → 1988
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:5 → 96
    DUF3398; Domain of unknown function (DUF3398)

  4. XM_028835224.1 → XP_028691057.1  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    F7AZW3, F7BL55, G7NG93
    Conserved Domains (3) summary
    cd08696
    Location:491 → 671
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1567 → 1988
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:5 → 96
    DUF3398; Domain of unknown function (DUF3398)

  5. XM_015117848.2 → XP_014973334.2  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    F7AZW3, F7BL55, G7NG93
    Conserved Domains (3) summary
    cd08696
    Location:491 → 671
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1567 → 1988
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:5 → 96
    DUF3398; Domain of unknown function (DUF3398)

  6. XM_015117846.2 → XP_014973332.2  dedicator of cytokinesis protein 8 isoform X2

    UniProtKB/TrEMBL
    F7BKY8, G7NG93
    Related
    ENSMMUP00000039150.3, ENSMMUT00000046106.3
    Conserved Domains (3) summary
    cd08696
    Location:543 → 723
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1619 → 2040
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:57 → 148
    DUF3398; Domain of unknown function (DUF3398)

  7. XM_015117850.2 → XP_014973336.2  dedicator of cytokinesis protein 8 isoform X4

    UniProtKB/TrEMBL
    A0A5F8AQR5
    Related
    ENSMMUP00000059016.2, ENSMMUT00000063350.2
    Conserved Domains (3) summary
    cd08696
    Location:491 → 671
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1535 → 1956
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:5 → 96
    DUF3398; Domain of unknown function (DUF3398)

  8. XM_015117849.2 → XP_014973335.2  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    F7AZW3, F7BL55, G7NG93
    Related
    ENSMMUP00000039148.3, ENSMMUT00000046104.3
    Conserved Domains (3) summary
    cd08696
    Location:491 → 671
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1567 → 1988
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8
    pfam11878
    Location:5 → 96
    DUF3398; Domain of unknown function (DUF3398)
Nucleotide Protein
Heading Accession and Version

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