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GHR growth hormone receptor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 697986, updated on 17-Aug-2024

Summary

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Official Symbol
GHRprovided by VGNC
Official Full Name
growth hormone receptorprovided by VGNC
Primary source
VGNC:VGNC:72922
See related
Ensembl:ENSMMUG00000001336
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GHR in Genome Data Viewer
Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (42354116..42668444)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (43085181..43437062)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like Neighboring gene F-box protein 4 Neighboring gene zinc finger protein 35 pseudogene Neighboring gene uncharacterized LOC114678777 Neighboring gene plasminogen activator inhibitor 1 RNA-binding protein pseudogene Neighboring gene uncharacterized LOC114678778 Neighboring gene coiled-coil domain containing 152 Neighboring gene selenoprotein P

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Monkey growth hormone (GH) receptor gene expression. Evidence for two mechanisms for the generation of the GH binding protein. Martini JF, et al. J Biol Chem, 1997 Jul 25. PMID 9228076
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of growth hormone receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
growth hormone receptor
Names
GH receptor
somatotropin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042667.1 → NP_001036132.1  growth hormone receptor precursor

    See identical proteins and their annotated locations for NP_001036132.1

    Status: PROVISIONAL

    Source sequence(s)
    U84589
    UniProtKB/Swiss-Prot
    P79194
    UniProtKB/TrEMBL
    G7MV63
    Related
    ENSMMUP00000059083.1, ENSMMUT00000068122.2
    Conserved Domains (3) summary
    cd00063
    Location:149 → 250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316 → 617
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49 → 127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    42354116..42668444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015139960.2 → XP_014995446.1  growth hormone receptor isoform X1

    UniProtKB/TrEMBL
    A0A1D5QFA6, A0A1D5RFI9, G7MV63
    Conserved Domains (3) summary
    cd00063
    Location:149 → 250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316 → 617
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49 → 127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_028849121.1 → XP_028704954.1  growth hormone receptor isoform X2

    UniProtKB/TrEMBL
    G7MV63
    Conserved Domains (3) summary
    cd00063
    Location:147 → 248
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:314 → 615
    GHBP; Growth hormone receptor binding
    cl21522
    Location:47 → 125
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  3. XM_015139959.2 → XP_014995445.1  growth hormone receptor isoform X1

    UniProtKB/TrEMBL
    A0A1D5QFA6, A0A1D5RFI9, G7MV63
    Conserved Domains (3) summary
    cd00063
    Location:149 → 250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316 → 617
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49 → 127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P79194.1 GenPept UniProtKB/Swiss-Prot:P79194

Gene LinkOut

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