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PROZ protein Z, vitamin K dependent plasma glycoprotein [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 696982, updated on 17-Aug-2024

Summary

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Official Symbol
PROZprovided by VGNC
Official Full Name
protein Z, vitamin K dependent plasma glycoproteinprovided by VGNC
Primary source
VGNC:VGNC:76428
See related
Ensembl:ENSMMUG00000001039
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PROZ in Genome Data Viewer
Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (94395207..94410759)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (94630061..94644881)

Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114673492 Neighboring gene coagulation factor VII Neighboring gene coagulation factor X Neighboring gene uncharacterized LOC106994402 Neighboring gene PCI domain containing 2 Neighboring gene cullin 4A Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vitamin K-dependent protein Z

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041770.1 Reference Mmul_10 Primary Assembly

    Range
    94395207..94410759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001087442.4 → XP_001087442.2  vitamin K-dependent protein Z isoform X1

    UniProtKB/TrEMBL
    F6SB17
    Related
    ENSMMUP00000001393.4, ENSMMUT00000001482.4
    Conserved Domains (4) summary
    smart00069
    Location:22 → 86
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    cd00054
    Location:95 → 123
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00089
    Location:189 → 341
    Trypsin
    pfam14670
    Location:136 → 165
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_028837371.1 → XP_028693204.1  vitamin K-dependent protein Z isoform X2

    UniProtKB/TrEMBL
    F6SB17
    Conserved Domains (4) summary
    smart00069
    Location:22 → 86
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    cd00054
    Location:95 → 123
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00089
    Location:170 → 322
    Trypsin
    pfam12662
    Location:128 → 150
    cEGF; Complement Clr-like EGF-like
Nucleotide Protein
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