SERPIND1 serpin family D member 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SERPIND1provided by VGNC
Official Full Name: serpin family D member 1provided by VGNC
Primary source: VGNC:VGNC:77357
Locus tag: EGK_02823
See related: Ensembl:ENSMMUG00000022169
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	10	NC_041763.1 (31557250..31571352)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	10	NC_027902.1 (62860697..62875118, complement)

Chromosome 10 - NC_041763.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

D22S1026 (e-PCR)
- UniSTS:59669

STS-M12849 (e-PCR)
- UniSTS:9301

RH27825 (e-PCR)
- UniSTS:90510

WI-7024 (e-PCR)
- UniSTS:32751

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in blood coagulation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: heparin cofactor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001265760.2 → NP_001252689.1 heparin cofactor 2 precursor

See identical proteins and their annotated locations for NP_001252689.1

Status: PROVISIONAL

Source sequence(s)

JV600210

UniProtKB/TrEMBL

A0A8J8XJH4, F6XIG8, G7N3B6

Conserved Domains (1) summary

cd02047
Location:62 → 497

HCII; Heparin cofactor II (HCII) inhibits thrombin, the final protease of the coagulation cascade. HCII is allosterically activated by binding to cell surface glycosaminoglycans (GAGs). The specificity of HCII for thrombin is conferred by a highly acidic ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041763.1 Reference Mmul_10 Primary Assembly

Range

31557250..31571352

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015149746.2 → XP_015005232.1 heparin cofactor 2 isoform X1

UniProtKB/TrEMBL

A0A8J8XJH4, F6XIG8, G7N3B6

Related

ENSMMUP00000029184.2, ENSMMUT00000031181.4

Conserved Domains (1) summary

cd02047
Location:62 → 497

HCII; Heparin cofactor II (HCII) inhibits thrombin, the final protease of the coagulation cascade. HCII is allosterically activated by binding to cell surface glycosaminoglycans (GAGs). The specificity of HCII for thrombin is conferred by a highly acidic ...