U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SOCS4 suppressor of cytokine signaling 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 696146, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
SOCS4provided by VGNC
Official Full Name
suppressor of cytokine signaling 4provided by VGNC
Primary source
VGNC:VGNC:77741
Locus tag
EGK_18204
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SOCS4 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (117135757..117153961)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (116988241..117006450)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene 40S ribosomal protein SA-like Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 like Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
suppressor of cytokine signaling 4

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193820.2 → NP_001180749.1  suppressor of cytokine signaling 4

    See identical proteins and their annotated locations for NP_001180749.1

    Status: PROVISIONAL

    Source sequence(s)
    QNVO02000421
    UniProtKB/TrEMBL
    A0A8J8YNV0, F6YVE7, H9ER10, H9Z1L1
    Conserved Domains (3) summary
    cd10385
    Location:275 → 375
    SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03738
    Location:384 → 439
    SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
    pfam12610
    Location:59 → 111
    SOCS; Suppressor of cytokine signalling

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    117135757..117153961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001087968.4 → XP_001087968.1  suppressor of cytokine signaling 4 isoform X1

    See identical proteins and their annotated locations for XP_001087968.1

    UniProtKB/TrEMBL
    A0A8J8YNV0, F6YVE7, H9ER10, H9Z1L1
    Conserved Domains (3) summary
    cd10385
    Location:275 → 375
    SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03738
    Location:384 → 439
    SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
    pfam12610
    Location:59 → 111
    SOCS; Suppressor of cytokine signalling

  2. XM_015143704.2 → XP_014999190.1  suppressor of cytokine signaling 4 isoform X1

    UniProtKB/TrEMBL
    A0A8J8YNV0, F6YVE7, H9ER10, H9Z1L1
    Conserved Domains (3) summary
    cd10385
    Location:275 → 375
    SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03738
    Location:384 → 439
    SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
    pfam12610
    Location:59 → 111
    SOCS; Suppressor of cytokine signalling

  3. XM_015143705.2 → XP_014999191.1  suppressor of cytokine signaling 4 isoform X1

    UniProtKB/TrEMBL
    A0A8J8YNV0, F6YVE7, H9ER10, H9Z1L1
    Conserved Domains (3) summary
    cd10385
    Location:275 → 375
    SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03738
    Location:384 → 439
    SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
    pfam12610
    Location:59 → 111
    SOCS; Suppressor of cytokine signalling
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials