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RIPK2 receptor interacting serine/threonine kinase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 695567, updated on 17-Aug-2024

Summary

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Official Symbol
RIPK2provided by VGNC
Official Full Name
receptor interacting serine/threonine kinase 2provided by VGNC
Primary source
VGNC:VGNC:76696
See related
Ensembl:ENSMMUG00000020725
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See RIPK2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (90153083..90190754)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (88262021..88298664)

Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999848 Neighboring gene uncharacterized LOC114680291 Neighboring gene uncharacterized LOC106999849 Neighboring gene U6 spliceosomal RNA Neighboring gene oxidative stress induced growth inhibitor family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables JUN kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-interacting serine/threonine-protein kinase 2
XP_001084687.1
XP_015001159.1
XP_015001160.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041761.1 Reference Mmul_10 Primary Assembly

    Range
    90153083..90190754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001084687.4 → XP_001084687.1  receptor-interacting serine/threonine-protein kinase 2 isoform X1

    See identical proteins and their annotated locations for XP_001084687.1

    UniProtKB/TrEMBL
    F6Q6C2, G7MZQ5
    Related
    ENSMMUP00000032057.2, ENSMMUT00000038968.3
    Conserved Domains (3) summary
    cd08786
    Location:438 → 524
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    smart00221
    Location:21 → 290
    STYKc; Protein kinase; unclassified specificity
    cl21453
    Location:20 → 303
    PKc_like; Protein Kinases, catalytic domain

  2. XM_015145673.2 → XP_015001159.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    G7MZQ5
    Conserved Domains (3) summary
    cd08786
    Location:408 → 494
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    smart00221
    Location:21 → 290
    STYKc; Protein kinase; unclassified specificity
    cl21453
    Location:20 → 303
    PKc_like; Protein Kinases, catalytic domain

  3. XM_015145674.2 → XP_015001160.1  receptor-interacting serine/threonine-protein kinase 2 isoform X3

    UniProtKB/TrEMBL
    H9F423
    Conserved Domains (2) summary
    cd08786
    Location:341 → 427
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cl21453
    Location:1 → 206
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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