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UHRF1 ubiquitin like with PHD and ring finger domains 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 695531, updated on 17-Aug-2024

Summary

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Official Symbol
UHRF1provided by VGNC
Official Full Name
ubiquitin like with PHD and ring finger domains 1provided by VGNC
Primary source
VGNC:VGNC:78713
See related
Ensembl:ENSMMUG00000012705
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See UHRF1 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (4841449..4898337)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (5063136..5119093)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106994613 Neighboring gene perilipin 3 Neighboring gene arrestin domain containing 5 Neighboring gene lysine demethylase 4B Neighboring gene translation initiation factor IF-2-like Neighboring gene protein tyrosine phosphatase receptor type S Neighboring gene 60S ribosomal protein L32 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of gene expression via chromosomal CpG island methylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase UHRF1
XP_001082762.1
XP_001083134.2
XP_014978040.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    4841449..4898337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001083134.4 → XP_001083134.2  E3 ubiquitin-protein ligase UHRF1 isoform X1

    Conserved Domains (6) summary
    cd01797
    Location:65 → 142
    NIRF_N; amino-terminal ubiquitin-like domain of Np95 and NIRF
    smart00213
    Location:67 → 138
    UBQ; Ubiquitin homologues
    cd00162
    Location:790 → 832
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd15616
    Location:383 → 429
    PHD_UHRF1; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1)
    pfam02182
    Location:483 → 650
    SAD_SRA; SAD/SRA domain
    pfam12148
    Location:197 → 350
    TTD; Tandem tudor domain within UHRF1

  2. XM_001082762.4 → XP_001082762.1  E3 ubiquitin-protein ligase UHRF1 isoform X2

    See identical proteins and their annotated locations for XP_001082762.1

    UniProtKB/TrEMBL
    A0A1D5Q791, F7DWN1
    Related
    ENSMMUP00000016682.2, ENSMMUT00000017814.4
    Conserved Domains (6) summary
    cd01797
    Location:1 → 78
    NIRF_N; amino-terminal ubiquitin-like domain of Np95 and NIRF
    smart00213
    Location:3 → 74
    UBQ; Ubiquitin homologues
    cd00162
    Location:726 → 768
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd15616
    Location:319 → 365
    PHD_UHRF1; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1)
    pfam02182
    Location:419 → 586
    SAD_SRA; SAD/SRA domain
    pfam12148
    Location:133 → 286
    TTD; Tandem tudor domain within UHRF1

  3. XM_015122554.2 → XP_014978040.1  E3 ubiquitin-protein ligase UHRF1 isoform X3

    Conserved Domains (5) summary
    cd00162
    Location:679 → 721
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd15616
    Location:272 → 318
    PHD_UHRF1; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1)
    pfam02182
    Location:372 → 539
    SAD_SRA; SAD/SRA domain
    pfam12148
    Location:86 → 239
    TTD; Tandem tudor domain within UHRF1
    cl00155
    Location:4 → 31
    UBQ; Ubiquitin-like proteins
Nucleotide Protein
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