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FBXW7 F-box and WD repeat domain containing 7 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 695101, updated on 17-Aug-2024

Summary

Official Symbol
FBXW7provided by VGNC
Official Full Name
F-box and WD repeat domain containing 7provided by VGNC
Primary source
VGNC:VGNC:72516
See related
Ensembl:ENSMMUG00000020330
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See FBXW7 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (149971005..150180717, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (152241055..152450787, complement)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678186 Neighboring gene uncharacterized LOC106998538 Neighboring gene microRNA mir-3140 Neighboring gene uncharacterized LOC696812 Neighboring gene 40S ribosomal protein S3a pseudogene

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in ubiquitin recycling IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
F-box/WD repeat-containing protein 7
Names
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257948.2NP_001244877.1  F-box/WD repeat-containing protein 7

    See identical proteins and their annotated locations for NP_001244877.1

    Status: PROVISIONAL

    Source sequence(s)
    JU335305
    UniProtKB/TrEMBL
    A0A1D5Q962, G7MS47
    Related
    ENSMMUP00000044580.1, ENSMMUT00000073363.2
    Conserved Domains (3) summary
    cd00200
    Location:374650
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:384419
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:281325
    F-box-like

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    149971005..150180717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015139321.2XP_014994807.1  F-box/WD repeat-containing protein 7 isoform X2

    UniProtKB/TrEMBL
    F6WGU1
    Related
    ENSMMUP00000026757.4, ENSMMUT00000028597.4
    Conserved Domains (4) summary
    COG2319
    Location:339679
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:346622
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam12937
    Location:253297
    F-box-like; F-box-like
    sd00039
    Location:356391
    7WD40; WD40 repeat [structural motif]
  2. XM_015139318.2XP_014994804.1  F-box/WD repeat-containing protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q962, G7MS47
    Conserved Domains (3) summary
    cd00200
    Location:374650
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:384419
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:281325
    F-box-like
  3. XM_015139317.2XP_014994803.1  F-box/WD repeat-containing protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q962, G7MS47
    Conserved Domains (3) summary
    cd00200
    Location:374650
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:384419
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:281325
    F-box-like
  4. XM_015139316.2XP_014994802.1  F-box/WD repeat-containing protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q962, G7MS47
    Conserved Domains (3) summary
    cd00200
    Location:374650
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:384419
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:281325
    F-box-like
  5. XM_015139322.2XP_014994808.2  F-box/WD repeat-containing protein 7 isoform X3

    UniProtKB/TrEMBL
    F6WGU9, H9FWQ0
    Related
    ENSMMUP00000026756.4, ENSMMUT00000028596.4
    Conserved Domains (3) summary
    cd00200
    Location:294570
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:304339
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:201245
    F-box-like
  6. XM_015139319.2XP_014994805.1  F-box/WD repeat-containing protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q962, G7MS47
    Conserved Domains (3) summary
    cd00200
    Location:374650
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:384419
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:281325
    F-box-like