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HELT helt bHLH transcription factor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694986, updated on 17-Aug-2024

Summary

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Official Symbol
HELTprovided by VGNC
Official Full Name
helt bHLH transcription factorprovided by VGNC
Primary source
VGNC:VGNC:73264
Locus tag
EGK_16283
See related
Ensembl:ENSMMUG00000001081
Gene type
protein coding
RefSeq status
INFERRED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HELT in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (182327305..182329408)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (185470627..185472723)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678456 Neighboring gene uncharacterized LOC114678457 Neighboring gene uncharacterized LOC106998607 Neighboring gene solute carrier family 25 member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hairy and enhancer of split-related protein HELT
Names
HES/HEY-like transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193735.1 → NP_001180664.1  hairy and enhancer of split-related protein HELT

    See identical proteins and their annotated locations for NP_001180664.1

    Status: INFERRED

    Source sequence(s)
    QNVO02000369
    UniProtKB/TrEMBL
    A0A8J8YG37, F6QM82, G7MSE2
    Related
    ENSMMUP00000001440.2, ENSMMUT00000001533.4
    Conserved Domains (2) summary
    pfam00010
    Location:57 → 151
    HLH; Helix-loop-helix DNA-binding domain
    pfam07527
    Location:172 → 212
    Hairy_orange; Hairy Orange

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    182327305..182329408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002804279.3 → XP_002804325.1  hairy and enhancer of split-related protein HELT isoform X1

    Conserved Domains (2) summary
    pfam00010
    Location:13 → 66
    HLH; Helix-loop-helix DNA-binding domain
    pfam07527
    Location:87 → 127
    Hairy_orange; Hairy Orange

  2. XM_015139559.2 → XP_014995045.1  hairy and enhancer of split-related protein HELT isoform X2

    Conserved Domains (2) summary
    pfam00010
    Location:13 → 66
    HLH; Helix-loop-helix DNA-binding domain
    pfam07527
    Location:86 → 126
    Hairy_orange; Hairy Orange
Nucleotide Protein
Heading Accession and Version

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