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SCN10A sodium voltage-gated channel alpha subunit 10 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694962, updated on 17-Aug-2024

Summary

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Official Symbol
SCN10Aprovided by VGNC
Official Full Name
sodium voltage-gated channel alpha subunit 10provided by VGNC
Primary source
VGNC:VGNC:76980
See related
Ensembl:ENSMMUG00000015827
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SCN10A in Genome Data Viewer
Location:
chromosome: 2
Exon count:
27
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (94148431..94249430, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (103931004..104032071)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L18a pseudogene Neighboring gene sodium voltage-gated channel alpha subunit 5 Neighboring gene uncharacterized LOC106996957 Neighboring gene sodium voltage-gated channel alpha subunit 11 Neighboring gene uncharacterized LOC106996956 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated sodium channel activity involved in cardiac muscle cell action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in AV node cell action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of atrial cardiac muscle cell membrane depolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart rate IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium channel protein type 10 subunit alpha
Names
sodium channel protein type 10 subunit alpha-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    94148431..94249430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015131317.2 → XP_014986803.2  sodium channel protein type 10 subunit alpha isoform X3

    UniProtKB/TrEMBL
    F7CEK9
    Conserved Domains (4) summary
    cd13433
    Location:1324 → 1376
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1056 → 1332
    Ion_trans; Ion transport protein
    pfam06512
    Location:809 → 1052
    Na_trans_assoc; Sodium ion transport-associated
    pfam16905
    Location:1641 → 1704
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_015131316.2 → XP_014986802.2  sodium channel protein type 10 subunit alpha isoform X2

    UniProtKB/TrEMBL
    F7CEK9
    Conserved Domains (5) summary
    cd13433
    Location:1421 → 1473
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1153 → 1429
    Ion_trans; Ion transport protein
    pfam06512
    Location:907 → 1149
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:459 → 608
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1738 → 1801
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  3. XM_015131314.2 → XP_014986800.2  sodium channel protein type 10 subunit alpha isoform X1

    UniProtKB/TrEMBL
    F7CEK9
    Related
    ENSMMUP00000020805.4, ENSMMUT00000022236.4
    Conserved Domains (5) summary
    cd13433
    Location:1422 → 1474
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1154 → 1430
    Ion_trans; Ion transport protein
    pfam06512
    Location:907 → 1150
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:459 → 608
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1739 → 1802
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein
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