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MYC MYC proto-oncogene, bHLH transcription factor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694626, updated on 28-Jan-2025

Summary

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Official Symbol
MYCprovided by VGNC
Official Full Name
MYC proto-oncogene, bHLH transcription factorprovided by VGNC
Primary source
VGNC:VGNC:109507
Locus tag
EGK_19271
See related
Ensembl:ENSMMUG00000014601
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
c-Myc
Orthologs
human mouse all
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Genomic context

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See MYC in Genome Data Viewer
Location:
chromosome: 8
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (128098629..128104634)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (127089827..127095160)

Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114680332 Neighboring gene uncharacterized LOC114680333 Neighboring gene uncharacterized LOC106999943 Neighboring gene U1 spliceosomal RNA Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Liu H, et al. Cell Stem Cell, 2008 Dec 4. PMID 19041774
  2. An empirical test for branch-specific positive selection. Nickel GC, et al. Genetics, 2008 Aug. PMID 18689901, Free PMC Article
  3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myc proto-oncogene protein
Names
proto-oncogene c-Myc
transcription factor p64
v-myc avian myelocytomatosis viral oncogene homolog
v-myc myelocytomatosis viral oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001435781.1 → NP_001422710.1  myc proto-oncogene protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    QNVO02000453

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041761.1 Reference Mmul_10 Primary Assembly

    Range
    128098629..128104634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028852119.1 → XP_028707952.1  myc proto-oncogene protein isoform X1

    UniProtKB/Swiss-Prot
    B8XIA5, H9Z974
    UniProtKB/TrEMBL
    G7N040
    Conserved Domains (2) summary
    cd11458
    Location:351 → 434
    bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins
    pfam01056
    Location:6 → 345
    Myc_N; Myc amino-terminal region

  2. XM_015145930.1 → XP_015001416.1  myc proto-oncogene protein isoform X1

    UniProtKB/Swiss-Prot
    B8XIA5, H9Z974
    UniProtKB/TrEMBL
    G7N040
    Related
    ENSMMUP00000056069.2, ENSMMUT00000058254.2
    Conserved Domains (2) summary
    cd11458
    Location:351 → 434
    bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins
    pfam01056
    Location:6 → 345
    Myc_N; Myc amino-terminal region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B8XIA5.2 GenPept UniProtKB/Swiss-Prot:B8XIA5

Gene LinkOut

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Molecular Biology Databases
Research Materials