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CLCN3 chloride voltage-gated channel 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694472, updated on 17-Aug-2024

Summary

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Official Symbol
CLCN3provided by VGNC
Official Full Name
chloride voltage-gated channel 3provided by VGNC
Primary source
VGNC:VGNC:71236
See related
Ensembl:ENSMMUG00000010228
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CLCN3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (166926472..167028107)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (169834713..169944460)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene SH3 domain containing ring finger 1 Neighboring gene NIMA related kinase 1 Neighboring gene histone PARylation factor 1 Neighboring gene prostaglandin E synthase 3 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
H(+)/Cl(-) exchange transporter 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    166926472..167028107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015139495.2 → XP_014994981.1  H(+)/Cl(-) exchange transporter 3 isoform X1

    UniProtKB/TrEMBL
    F6S3L2, H9EPI1, H9YYH2
    Related
    ENSMMUP00000013392.4, ENSMMUT00000014298.4
    Conserved Domains (2) summary
    cd03684
    Location:136 → 642
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:653 → 803
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

  2. XM_015139499.2 → XP_014994985.1  H(+)/Cl(-) exchange transporter 3 isoform X3

    UniProtKB/TrEMBL
    A0A1D5QNR1, H9EPI2, H9YYH3
    Related
    ENSMMUP00000049687.2, ENSMMUT00000054195.2
    Conserved Domains (2) summary
    cd03684
    Location:136 → 642
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:653 → 803
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

  3. XM_015139497.2 → XP_014994983.1  H(+)/Cl(-) exchange transporter 3 isoform X2

    UniProtKB/TrEMBL
    H9YYH2
    Related
    ENSMMUP00000048797.2, ENSMMUT00000077657.2
    Conserved Domains (2) summary
    cd03684
    Location:109 → 615
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:626 → 776
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

  4. XM_015139501.2 → XP_014994987.1  H(+)/Cl(-) exchange transporter 3 isoform X4

    UniProtKB/TrEMBL
    A0A1D5Q4G1, H9YYH3
    Related
    ENSMMUP00000042925.2, ENSMMUT00000071924.2
    Conserved Domains (2) summary
    cd03684
    Location:109 → 615
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:626 → 776
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
Nucleotide Protein
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