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DAPK1 death associated protein kinase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694315, updated on 17-Aug-2024

Summary

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Official Symbol
DAPK1provided by VGNC
Official Full Name
death associated protein kinase 1provided by VGNC
Primary source
VGNC:VGNC:71732
Locus tag
EGK_07830
See related
Ensembl:ENSMMUG00000017053
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DAPK1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
30
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (102623713..102833012)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (103698145..103908854)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672833 Neighboring gene small nucleolar RNA SNORA26 Neighboring gene uncharacterized LOC114672835 Neighboring gene uncharacterized LOC114672834 Neighboring gene eukaryotic translation initiation factor 3 subunit J-like Neighboring gene cathepsin L

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables TIR domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MyD88-dependent toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
death-associated protein kinase 1
NP_001244717.1
XP_014973500.1
XP_014973501.1
XP_028690046.1
XP_028690047.1
XP_028690048.1
XP_028690049.1
XP_028690050.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257788.1 → NP_001244717.1  death-associated protein kinase 1

    See identical proteins and their annotated locations for NP_001244717.1

    Status: PROVISIONAL

    Source sequence(s)
    JU321974
    UniProtKB/TrEMBL
    A0A5F7ZJJ0, A0A8J8XUA8, F7HLL1, G7NGF7
    Related
    ENSMMUP00000065775.1, ENSMMUT00000080452.1
    Conserved Domains (7) summary
    smart00220
    Location:13 → 275
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00204
    Location:505 → 629
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    pfam12796
    Location:416 → 508
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:513 → 564
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    102623713..102833012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015118014.2 → XP_014973500.1  death-associated protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZJJ0, A0A8J8XUA8, F7HLL1, G7NGF7
    Conserved Domains (7) summary
    smart00220
    Location:13 → 275
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00204
    Location:505 → 629
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    pfam12796
    Location:416 → 508
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:513 → 564
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

  2. XM_028834213.1 → XP_028690046.1  death-associated protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F7HLL1, F7HNL1
    Conserved Domains (5) summary
    PLN03192
    Location:515 → 768
    PLN03192; Voltage-dependent potassium channel; Provisional
    PHA03100
    Location:367 → 639
    PHA03100; ankyrin repeat protein; Provisional
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

  3. XM_028834215.1 → XP_028690048.1  death-associated protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F7HLL1, F7HNL1
    Conserved Domains (5) summary
    PLN03192
    Location:515 → 768
    PLN03192; Voltage-dependent potassium channel; Provisional
    PHA03100
    Location:367 → 639
    PHA03100; ankyrin repeat protein; Provisional
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

  4. XM_028834216.1 → XP_028690049.1  death-associated protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F7HLL1, F7HNL1
    Conserved Domains (5) summary
    PLN03192
    Location:515 → 768
    PLN03192; Voltage-dependent potassium channel; Provisional
    PHA03100
    Location:367 → 639
    PHA03100; ankyrin repeat protein; Provisional
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

  5. XM_015118015.2 → XP_014973501.1  death-associated protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZJJ0, A0A8J8XUA8, F7HLL1, G7NGF7
    Conserved Domains (7) summary
    smart00220
    Location:13 → 275
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00204
    Location:505 → 629
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    pfam12796
    Location:416 → 508
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:513 → 564
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

  6. XM_028834214.1 → XP_028690047.1  death-associated protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F7HLL1, F7HNL1
    Related
    ENSMMUP00000022443.4, ENSMMUT00000023978.4
    Conserved Domains (5) summary
    PLN03192
    Location:515 → 768
    PLN03192; Voltage-dependent potassium channel; Provisional
    PHA03100
    Location:367 → 639
    PHA03100; ankyrin repeat protein; Provisional
    cd08782
    Location:1308 → 1393
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    cd14194
    Location:7 → 275
    STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
    sd00045
    Location:412 → 442
    ANK; ANK repeat [structural motif]

  7. XM_028834217.1 → XP_028690050.1  death-associated protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    F7HLL1
    Conserved Domains (7) summary
    PLN03192
    Location:370 → 623
    PLN03192; Voltage-dependent potassium channel; Provisional
    PHA03100
    Location:222 → 494
    PHA03100; ankyrin repeat protein; Provisional
    cd08782
    Location:1163 → 1248
    Death_DAPK1; Death domain found in death-associated protein kinase 1
    sd00045
    Location:267 → 297
    ANK; ANK repeat [structural motif]
    pfam16095
    Location:860 → 1028
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:1 → 130
    PKc_like; Protein Kinases, catalytic domain
    cl21455
    Location:644 → 745
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version

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