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DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694048, updated on 17-Aug-2024

Summary

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Official Symbol
DIS3provided by VGNC
Official Full Name
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonucleaseprovided by VGNC
Primary source
VGNC:VGNC:71687
See related
Ensembl:ENSMMUG00000000787
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DIS3 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (54538574..54568415, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (53880114..53916217, complement)

Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA9 Neighboring gene mitotic spindle organizing protein 1 Neighboring gene BORA aurora kinase A activator Neighboring gene progesterone immunomodulatory binding factor 1 Neighboring gene uncharacterized LOC106994306 Neighboring gene 26S proteasome non-ATPase regulatory subunit 10 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • KIAA1008

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in rRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cytoplasmic exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of nuclear exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
exosome complex exonuclease RRP44
Names
DIS3 mitotic control homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041770.1 Reference Mmul_10 Primary Assembly

    Range
    54538574..54568415 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015121173.2 → XP_014976659.2  exosome complex exonuclease RRP44 isoform X1

    UniProtKB/TrEMBL
    F6RAL3, G7NJF1, H9YYI3
    Related
    ENSMMUP00000001068.4, ENSMMUT00000001139.4
    Conserved Domains (2) summary
    COG0557
    Location:195 → 930
    VacB; Exoribonuclease R [Transcription]
    cd09862
    Location:9 → 197
    PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

  2. XM_001084036.4 → XP_001084036.2  exosome complex exonuclease RRP44 isoform X2

    UniProtKB/TrEMBL
    G7NJF1, H9YYI3
    Conserved Domains (2) summary
    COG0557
    Location:165 → 900
    VacB; Exoribonuclease R [Transcription]
    cd09862
    Location:9 → 167
    PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

  3. XM_015121174.2 → XP_014976660.2  exosome complex exonuclease RRP44 isoform X3

    UniProtKB/TrEMBL
    G7NJF1, H9YYI3
    Conserved Domains (2) summary
    COG0557
    Location:33 → 768
    VacB; Exoribonuclease R [Transcription]
    cl28905
    Location:5 → 35
    PIN_SF; PIN (PilT N terminus) domain: Superfamily
Nucleotide Protein
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