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NOS1 nitric oxide synthase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 693781, updated on 17-Aug-2024

Summary

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Official Symbol
NOS1provided by VGNC
Official Full Name
nitric oxide synthase 1provided by VGNC
Primary source
VGNC:VGNC:75368
See related
Ensembl:ENSMMUG00000014027
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See NOS1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
29
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (116946412..117098744, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (117289857..117435491, complement)

Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107001038 Neighboring gene F-box protein 21 Neighboring gene uncharacterized LOC114670967 Neighboring gene uncharacterized LOC114670968 Neighboring gene kinase suppressor of ras 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nitric oxide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nitric oxide synthase, brain
Names
nitric oxide synthase 1 (neuronal)
XP_028685784.1
XP_028685785.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041764.1 Reference Mmul_10 Primary Assembly

    Range
    116946412..117098744 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028829951.1 → XP_028685784.1  nitric oxide synthase, brain

    UniProtKB/TrEMBL
    F7AVJ6, F7AVK5
    Related
    ENSMMUP00000018436.4, ENSMMUT00000019691.4
    Conserved Domains (5) summary
    cd06202
    Location:1001 → 1404
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:305 → 716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:15 → 98
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR02037
    Location:41 → 197
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family
    pfam00258
    Location:762 → 935
    Flavodoxin_1

  2. XM_028829952.1 → XP_028685785.1  nitric oxide synthase, brain

    UniProtKB/TrEMBL
    F7AVJ6, F7AVK5
    Related
    ENSMMUP00000068918.1, ENSMMUT00000081726.1
    Conserved Domains (5) summary
    cd06202
    Location:1001 → 1404
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:305 → 716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:15 → 98
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR02037
    Location:41 → 197
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family
    pfam00258
    Location:762 → 935
    Flavodoxin_1
Nucleotide Protein
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