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AFDN afadin, adherens junction formation factor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 693560, updated on 17-Aug-2024

Summary

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Official Symbol
AFDNprovided by VGNC
Official Full Name
afadin, adherens junction formation factorprovided by VGNC
Primary source
VGNC:VGNC:69818
See related
Ensembl:ENSMMUG00000021044
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See AFDN in Genome Data Viewer
Location:
chromosome: 4
Exon count:
35
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (2688655..2830526, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (169274271..169416161)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 25 Neighboring gene putative uncharacterized protein KIF25-AS1 Neighboring gene skin secretory protein xP2 Neighboring gene uncharacterized LOC114677437 Neighboring gene uncharacterized LOC114677436 Neighboring gene putative uncharacterized protein AFDN-DT Neighboring gene uncharacterized LOC114677438

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of protein localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
afadin
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    2688655..2830526 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015137697.2 → XP_014993183.2  afadin isoform X4

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1466 → 1699
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  2. XM_028846970.1 → XP_028702803.1  afadin isoform X22

    UniProtKB/TrEMBL
    F7HG08
    Related
    ENSMMUP00000027697.4, ENSMMUT00000029596.4
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:597 → 925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1001 → 1083
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1452 → 1673
    DUF4670; Domain of unknown function (DUF4670)

  3. XM_015137704.2 → XP_014993190.2  afadin isoform X13

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:597 → 925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1452 → 1685
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1001 → 1083
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  4. XM_015137710.2 → XP_014993196.2  afadin isoform X20

    UniProtKB/TrEMBL
    F7HG08
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1460 → 1679
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1009 → 1091
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  5. XM_015137701.2 → XP_014993187.2  afadin isoform X9

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1460 → 1693
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1009 → 1091
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  6. XM_015137708.2 → XP_014993194.2  afadin isoform X18

    UniProtKB/TrEMBL
    F7HG08
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1686
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  7. XM_015137703.2 → XP_014993189.2  afadin isoform X12

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1686
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  8. XM_028846968.1 → XP_028702801.1  afadin isoform X17

    UniProtKB/TrEMBL
    F7HG08
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1688
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  9. XM_015137702.2 → XP_014993188.2  afadin isoform X11

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1688
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  10. XM_028846966.1 → XP_028702799.1  afadin isoform X8

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam17380
    Location:1417 → 1694
    DUF5401; Family of unknown function (DUF5401)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  11. XM_015137696.2 → XP_014993182.2  afadin isoform X3

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1699
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  12. XM_015137699.2 → XP_014993185.2  afadin isoform X6

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam17380
    Location:1417 → 1695
    DUF5401; Family of unknown function (DUF5401)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  13. XM_015137706.2 → XP_014993192.2  afadin isoform X16

    UniProtKB/TrEMBL
    F7HG07, G7MR78
    Related
    ENSMMUP00000027696.4, ENSMMUT00000029595.4
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1700
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  14. XM_015137698.2 → XP_014993184.2  afadin isoform X5

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1700
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  15. XM_015137694.2 → XP_014993180.2  afadin isoform X1

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1467 → 1700
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  16. XM_015137713.2 → XP_014993199.2  afadin isoform X23

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1443 → 1664
    DUF4670; Domain of unknown function (DUF4670)

  17. XM_015137705.2 → XP_014993191.2  afadin isoform X15

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1443 → 1676
    DUF4670; Domain of unknown function (DUF4670)

  18. XM_015137700.2 → XP_014993186.2  afadin isoform X7

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:416 → 498
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:610 → 938
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1465 → 1698
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1014 → 1096
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  19. XM_028846969.1 → XP_028702802.1  afadin isoform X21

    UniProtKB/TrEMBL
    F7HG08
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1459 → 1678
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  20. XM_015137712.2 → XP_014993198.2  afadin isoform X14

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1459 → 1678
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  21. XM_015137709.2 → XP_014993195.2  afadin isoform X19

    UniProtKB/TrEMBL
    F7HG08
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1459 → 1680
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  22. XM_028846967.1 → XP_028702800.1  afadin isoform X10

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1459 → 1692
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin

  23. XM_015137695.2 → XP_014993181.2  afadin isoform X2

    UniProtKB/TrEMBL
    F7HG05
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    pfam15709
    Location:1466 → 1699
    DUF4670; Domain of unknown function (DUF4670)
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
Nucleotide Protein
Heading Accession and Version

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