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PKN2 protein kinase N2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 693505, updated on 17-Aug-2024

Summary

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Official Symbol
PKN2provided by VGNC
Official Full Name
protein kinase N2provided by VGNC
Primary source
VGNC:VGNC:76015
See related
Ensembl:ENSMMUG00000020588
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PKN2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (135623964..135787033, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (88889903..89052449)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999568 Neighboring gene general transcription factor IIB Neighboring gene U6 spliceosomal RNA Neighboring gene transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) pseudogene Neighboring gene COP9 signalosome complex subunit 6 pseudogene Neighboring gene uncharacterized LOC106999565

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase N2
Names
serine/threonine-protein kinase N2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    135623964..135787033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028831697.1 → XP_028687530.1  serine/threonine-protein kinase N2 isoform X3

    UniProtKB/TrEMBL
    A0A1D5QYM8
    Conserved Domains (5) summary
    cd08687
    Location:329 → 410
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:42 → 107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209 → 282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd05589
    Location:594 → 919
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:127 → 201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

  2. XM_015144453.2 → XP_014999939.1  serine/threonine-protein kinase N2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5QYM8, F7C0E0
    Related
    ENSMMUP00000027100.4, ENSMMUT00000028962.4
    Conserved Domains (5) summary
    cd11622
    Location:42 → 107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209 → 282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd05589
    Location:608 → 933
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:127 → 201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
    cl14603
    Location:389 → 471
    C2; C2 domain

  3. XM_015144447.2 → XP_014999933.1  serine/threonine-protein kinase N2 isoform X1

    UniProtKB/TrEMBL
    A0A1D5QYM8, H9FX45
    Related
    ENSMMUP00000053159.2, ENSMMUT00000063363.2
    Conserved Domains (5) summary
    cd08687
    Location:389 → 472
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:42 → 107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209 → 282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd05589
    Location:656 → 981
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:127 → 201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
Nucleotide Protein
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