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Mrpl57 mitochondrial ribosomal protein L57 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691814, updated on 27-Nov-2024

Summary

Official Symbol
Mrpl57provided by RGD
Official Full Name
mitochondrial ribosomal protein L57provided by RGD
Primary source
RGD:1594654
See related
EnsemblRapid:ENSRNOG00000081514 AllianceGenome:RGD:1594654
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mrp63
Summary
Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL57 (mitochondrial ribosomal protein L57). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 222.9), Kidney (RPKM 218.7) and 9 other tissues See more
Orthologs
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Genomic context

See Mrpl57 in Genome Data Viewer
Location:
15p12
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (36086457..36087319)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (31970904..31971766)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (38096994..38097856)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482228 Neighboring gene Sin3A associated protein 18 Neighboring gene spindle and kinetochore associated complex subunit 3 Neighboring gene zinc finger DHHC-type palmitoyltransferase 20 Neighboring gene uncharacterized LOC134482124 Neighboring gene mitochondrial calcium uptake 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondrial ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large ribosomal subunit protein mL63
Names
mitochondrial ribosomal protein 63
ribosomal protein 63, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109649.2NP_001103119.1  large ribosomal subunit protein mL63

    See identical proteins and their annotated locations for NP_001103119.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000015
    UniProtKB/TrEMBL
    A0A8I6AJG2, B2RZD0
    Related
    ENSRNOP00000111579.1, ENSRNOT00000165080.1
    Conserved Domains (1) summary
    pfam14978
    Location:14101
    MRP-63; Mitochondrial ribosome protein 63

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    36086457..36087319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)