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Eri2 ERI1 exoribonuclease family member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691484, updated on 4-Jan-2025

Summary

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Official Symbol
Eri2provided by RGD
Official Full Name
ERI1 exoribonuclease family member 2provided by RGD
Primary source
RGD:1583889
See related
EnsemblRapid:ENSRNOG00000014673 AllianceGenome:RGD:1583889
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Exod1
Summary
Predicted to enable 3'-5'-RNA exonuclease activity. Orthologous to human ERI2 (ERI1 exoribonuclease family member 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 196.4), Liver (RPKM 107.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Eri2 in Genome Data Viewer
Location:
1q35
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (183551919..183600134, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (174140831..174168757, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (189540145..189549891, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene protein disulfide isomerase-like, testis expressed Neighboring gene uncharacterized LOC134483776 Neighboring gene acyl-CoA synthetase medium-chain family member 4 Neighboring gene THUMP domain containing 1 Neighboring gene acyl-CoA synthetase medium-chain family member 3 Neighboring gene RNA exonuclease 5 Neighboring gene defective in cullin neddylation 1 domain containing 3 Neighboring gene LYR motif containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene dynein, axonemal, heavy chain 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ERI1 exoribonuclease 2
Names
exonuclease domain containing 1
exonuclease domain containing 1-like
exoribonuclease 2
NP_001178043.1
XP_038947521.1
XP_038947532.1
XP_038947536.1
XP_063130950.1
XP_063130951.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191114.1 → NP_001178043.1  ERI1 exoribonuclease 2

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    D4A625
    Related
    ENSRNOP00000019747.5, ENSRNOT00000019747.8
    Conserved Domains (2) summary
    cd06133
    Location:37 → 230
    ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins
    pfam06839
    Location:592 → 640
    zf-GRF; GRF zinc finger

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    183551919..183600134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039091593.2 → XP_038947521.1  ERI1 exoribonuclease 2 isoform X1

    Conserved Domains (2) summary
    cd06133
    Location:37 → 254
    ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins
    pfam06839
    Location:616 → 663
    zf-GRF; GRF zinc finger

  2. XM_063274880.1 → XP_063130950.1  ERI1 exoribonuclease 2 isoform X4

    UniProtKB/TrEMBL
    A0A8I6A9P0

  3. XM_063274881.1 → XP_063130951.1  ERI1 exoribonuclease 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6A9P0

  4. XM_039091604.2 → XP_038947532.1  ERI1 exoribonuclease 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A9P0
    Conserved Domains (1) summary
    cd06133
    Location:37 → 254
    ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins

  5. XM_039091608.2 → XP_038947536.1  ERI1 exoribonuclease 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I6A9P0
    Related
    ENSRNOP00000089192.1, ENSRNOT00000106664.2
    Conserved Domains (1) summary
    cd06133
    Location:37 → 254
    ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins

RNA

  1. XR_010058148.1 RNA Sequence

  2. XR_010058149.1 RNA Sequence

  3. XR_005492892.2 RNA Sequence

  4. XR_005492893.2 RNA Sequence

  5. XR_010058185.1 RNA Sequence

  6. XR_005492882.2 RNA Sequence

  7. XR_010058147.1 RNA Sequence

  8. XR_010058143.1 RNA Sequence

  9. XR_010058180.1 RNA Sequence

  10. XR_010058182.1 RNA Sequence

  11. XR_005492899.2 RNA Sequence

  12. XR_010058153.1 RNA Sequence

  13. XR_010058151.1 RNA Sequence

  14. XR_010058155.1 RNA Sequence

  15. XR_010058150.1 RNA Sequence

  16. XR_010058163.1 RNA Sequence

  17. XR_010058191.1 RNA Sequence

  18. XR_005492896.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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