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Chst14 carbohydrate sulfotransferase 14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691394, updated on 27-Nov-2024

Summary

Official Symbol
Chst14provided by RGD
Official Full Name
carbohydrate sulfotransferase 14provided by RGD
Primary source
RGD:1585023
See related
AllianceGenome:RGD:1585023
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate proteoglycan metabolic process. Predicted to act upstream of or within dermatan sulfate biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Chst14 in Genome Data Viewer
Location:
3q35
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (126370348..126372405)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (105916481..105918538)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (110734105..110736162)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486300 Neighboring gene bromo adjacent homology domain containing 1 Neighboring gene uncharacterized LOC134486301 Neighboring gene coiled-coil domain containing 32

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables dermatan 4-sulfotransferase ISO
Inferred from Sequence Orthology
more info
 
enables sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in carbohydrate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within dermatan sulfate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in dermatan sulfate proteoglycan metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in dermatan sulfate proteoglycan metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
carbohydrate sulfotransferase 14
Names
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
dermatan 4 sulfotransferase 1
NP_001103109.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109639.1NP_001103109.1  carbohydrate sulfotransferase 14

    See identical proteins and their annotated locations for NP_001103109.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473949
    UniProtKB/TrEMBL
    B2GV63, M0R8Y4
    Conserved Domains (1) summary
    pfam03567
    Location:144364
    Sulfotransfer_2; Sulfotransferase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    126370348..126372405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)