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Pex11g peroxisomal biogenesis factor 11 gamma [ Mus musculus (house mouse) ]

Gene ID: 69129, updated on 27-Nov-2024

Summary

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Official Symbol
Pex11gprovided by MGI
Official Full Name
peroxisomal biogenesis factor 11 gammaprovided by MGI
Primary source
MGI:MGI:1920905
See related
Ensembl:ENSMUSG00000069633 AllianceGenome:MGI:1920905
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pex11c; Pex11gamma; 1810022F11Rik; 1810049N02Rik
Summary
Predicted to be involved in peroxisome fission and regulation of peroxisome size. Predicted to be located in peroxisome. Predicted to be part of protein-containing complex. Predicted to be active in peroxisomal membrane. Orthologous to human PEX11G (peroxisomal biogenesis factor 11 gamma). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in testis adult (RPKM 14.0), liver adult (RPKM 13.6) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Pex11g in Genome Data Viewer
Location:
8 A1.1; 8 1.92 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (3507105..3517648, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (3457105..3467648, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:3354554-3354663 Neighboring gene predicted gene, 30369 Neighboring gene Rho/Rac guanine nucleotide exchange factor 18 Neighboring gene STARR-seq mESC enhancer starr_20578 Neighboring gene predicted gene, 46029 Neighboring gene STARR-positive B cell enhancer ABC_E10487 Neighboring gene stabilizer of axonemal microtubules 5 Neighboring gene zinc finger protein 358 Neighboring gene mucolipin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation. Li X, et al. Mol Cell Biol, 2002 Dec. PMID 12417726, Free PMC Article
  2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in peroxisome fission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peroxisome fission IEA
Inferred from Electronic Annotation
more info
  
involved_in peroxisome fission ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of peroxisome size IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of peroxisome size ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisomal membrane ISO
Inferred from Sequence Orthology
more info
  
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
  
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
peroxisomal membrane protein 11C
Names
PEX11-gamma
peroxin-11C
peroxisomal biogenesis factor 11c
protein PEX11 homolog gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368376.1 → NP_001355305.1  peroxisomal membrane protein 11C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC169677

  2. NM_001368377.1 → NP_001355306.1  peroxisomal membrane protein 11C isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC169677

  3. NM_001368378.1 → NP_001355307.1  peroxisomal membrane protein 11C isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC169677

  4. NM_026951.3 → NP_081227.1  peroxisomal membrane protein 11C isoform 2

    See identical proteins and their annotated locations for NP_081227.1

    Status: VALIDATED

    Source sequence(s)
    AC169677
    Consensus CDS
    CCDS22061.1
    UniProtKB/Swiss-Prot
    Q6P6M5, Q9D8P0, Q9D8X4
    Related
    ENSMUSP00000004686.7, ENSMUST00000004686.13
    Conserved Domains (1) summary
    pfam05648
    Location:4 → 230
    PEX11; Peroxisomal biogenesis factor 11 (PEX11)

  5. NM_028594.1 → NP_082870.1  peroxisomal membrane protein 11C isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC169677
    Consensus CDS
    CCDS90364.1
    Related
    ENSMUSP00000106710.4, ENSMUST00000111081.10

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    3507105..3517648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P6M5.2 GenPept UniProtKB/Swiss-Prot:Q6P6M5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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