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Catip ciliogenesis associated TTC17 interacting protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 690437, updated on 9-Dec-2024

Summary

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Official Symbol
Catipprovided by RGD
Official Full Name
ciliogenesis associated TTC17 interacting proteinprovided by RGD
Primary source
RGD:1596071
See related
EnsemblRapid:ENSRNOG00000037835 AllianceGenome:RGD:1596071
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in actin filament polymerization and cilium organization. Located in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 54. Orthologous to human CATIP (ciliogenesis associated TTC17 interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Testes (RPKM 34.8), Lung (RPKM 30.1) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Catip in Genome Data Viewer
Location:
9q33
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (83395095..83402743)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (75945960..75953618)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (81644239..81652045)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene angio-associated, migratory cell protein Neighboring gene PNKD metallo-beta-lactamase domain containing Neighboring gene transmembrane BAX inhibitor motif containing 1 Neighboring gene solute carrier family 11 member 1 Neighboring gene CTD small phosphatase 1 Neighboring gene microRNA 26b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. C2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and human. Bontems F, et al. PLoS One, 2014. PMID 24475127, Free PMC Article
  2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in actin filament polymerization IEA
Inferred from Electronic Annotation
more info
  
involved_in actin filament polymerization ISO
Inferred from Sequence Orthology
more info
  
involved_in actin filament polymerization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in cell projection organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cilium organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cilium organization ISO
Inferred from Sequence Orthology
more info
  
involved_in cilium organization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
located_in actin cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
ciliogenesis-associated TTC17-interacting protein
Names
Ciliogenesis-associated TTC17-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419706.1 → NP_001406635.1  ciliogenesis-associated TTC17-interacting protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    D4A843
    Related
    ENSRNOP00000066656.4, ENSRNOT00000071700.4

  2. NM_001419707.1 → NP_001406636.1  ciliogenesis-associated TTC17-interacting protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I5ZX41, D4A843
    Related
    ENSRNOP00000083527.2, ENSRNOT00000108303.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    83395095..83402743
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017596825.3 → XP_017452314.1  ciliogenesis-associated TTC17-interacting protein isoform X1

    UniProtKB/TrEMBL
    A0A0H2UI37, D4A843

  2. XM_039084641.2 → XP_038940569.1  ciliogenesis-associated TTC17-interacting protein isoform X3

  3. XM_039084639.2 → XP_038940567.1  ciliogenesis-associated TTC17-interacting protein isoform X2

    UniProtKB/TrEMBL
    D4A843
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M0RAU5.1 GenPept UniProtKB/Swiss-Prot:M0RAU5

Gene LinkOut

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