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Tex12 testis expressed 12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690393, updated on 9-Dec-2024

Summary

Official Symbol
Tex12provided by RGD
Official Full Name
testis expressed 12provided by RGD
Primary source
RGD:1597300
See related
EnsemblRapid:ENSRNOG00000049470 AllianceGenome:RGD:1597300
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in synaptonemal complex assembly. Predicted to act upstream of or within meiotic DNA repair synthesis. Predicted to be located in synaptonemal complex. Predicted to be active in central element. Orthologous to human TEX12 (testis expressed 12). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Adrenal (RPKM 62.7), Spleen (RPKM 28.0) and 9 other tissues See more
Orthologs
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Genomic context

See Tex12 in Genome Data Viewer
Location:
8q23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (59804662..59809595, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (50908161..50913202, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (54991501..54999454, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene 6-pyruvoyl-tetrahydropterin synthase Neighboring gene beta-carotene oxygenase 2 Neighboring gene interleukin 18 Neighboring gene succinate dehydrogenase complex subunit D Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene NKAP domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within meiotic DNA repair synthesis ISO
Inferred from Sequence Orthology
more info
 
involved_in synaptonemal complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within synaptonemal complex assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in central element IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in central element ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
located_in synaptonemal complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
testis-expressed protein 12
Names
testis expressed gene 12
testis-expressed sequence 12 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191106.2NP_001178035.1  testis-expressed protein 12

    See identical proteins and their annotated locations for NP_001178035.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A6J4D8, D4A057
    Related
    ENSRNOP00000013014.4, ENSRNOT00000013014.7
    Conserved Domains (1) summary
    pfam15219
    Location:28122
    TEX12; Testis-expressed 12

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    59804662..59809595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008766338.4XP_008764560.1  testis-expressed protein 12 isoform X1

    See identical proteins and their annotated locations for XP_008764560.1

    UniProtKB/TrEMBL
    A6J4D8, D4A057
    Conserved Domains (1) summary
    pfam15219
    Location:28122
    TEX12; Testis-expressed 12