U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tmem223 transmembrane protein 223 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690285, updated on 27-Nov-2024

Summary

Official Symbol
Tmem223provided by RGD
Official Full Name
transmembrane protein 223provided by RGD
Primary source
RGD:1582829
See related
EnsemblRapid:ENSRNOG00000019266 AllianceGenome:RGD:1582829
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be active in mitochondrial inner membrane. Orthologous to human TMEM223 (transmembrane protein 223). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 291.8), Kidney (RPKM 286.5) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tmem223 in Genome Data Viewer
Location:
1q43
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (215097835..215099196)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (205668716..205670077)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (224970807..224972168)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene syntaxin 5 Neighboring gene nuclear RNA export factor 1 Neighboring gene transmembrane protein 179B Neighboring gene interferon-induced transmembrane protein 2-like Neighboring gene TATA-box binding protein associated factor 6 like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mitochondrial ribosome binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191104.1NP_001178033.1  transmembrane protein 223

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    D4AC93
    Related
    ENSRNOP00000026141.2, ENSRNOT00000026141.6
    Conserved Domains (1) summary
    pfam14640
    Location:32197
    TMEM223; Transmembrane protein 223

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    215097835..215099196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)