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Lsmem2 leucine-rich single-pass membrane protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 689621, updated on 27-Nov-2024

Summary

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Official Symbol
Lsmem2provided by RGD
Official Full Name
leucine-rich single-pass membrane protein 2provided by RGD
Primary source
RGD:1589957
See related
EnsemblRapid:ENSRNOG00000052634 AllianceGenome:RGD:1589957
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in membrane. Orthologous to human LSMEM2 (leucine rich single-pass membrane protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 57.6), Heart (RPKM 51.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Lsmem2 in Genome Data Viewer
Location:
8q32
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (117144498..117149300, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (108265855..108270656, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (116348406..116353092, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene hyaluronidase 2 Neighboring gene hyaluronidase 1 Neighboring gene N(alpha)-acetyltransferase 80, NatH catalytic subunit Neighboring gene hyaluronidase 3 Neighboring gene interferon-related developmental regulator 2 Neighboring gene semaphorin 3B Neighboring gene uncharacterized LOC120094260 Neighboring gene G protein subunit alpha i2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
leucine-rich single-pass membrane protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430399.1 → NP_001417328.1  leucine-rich single-pass membrane protein 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8I6A425

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    117144498..117149300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001071401.5 → XP_001071401.1  leucine-rich single-pass membrane protein 2 isoform X2

    Related
    ENSRNOP00000108614.1, ENSRNOT00000157156.1
    Conserved Domains (1) summary
    pfam15833
    Location:1 → 148
    DUF4714; Domain of unknown function (DUF4714)

  2. XM_039082622.1 → XP_038938550.1  leucine-rich single-pass membrane protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A0G2KAD9
    Related
    ENSRNOP00000075362.3, ENSRNOT00000087306.3
    Conserved Domains (1) summary
    pfam15833
    Location:72 → 217
    DUF4714; Domain of unknown function (DUF4714)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials