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Aldh3b2 aldehyde dehydrogenase 3 family, member B2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688800, updated on 27-Nov-2024

Summary

Official Symbol
Aldh3b2provided by RGD
Official Full Name
aldehyde dehydrogenase 3 family, member B2provided by RGD
Primary source
RGD:1584166
See related
EnsemblRapid:ENSRNOG00000068138 AllianceGenome:RGD:1584166
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable aldehyde dehydrogenase [NAD(P)+] activity. Predicted to be involved in cellular aldehyde metabolic process. Orthologous to human ALDH3B2 (aldehyde dehydrogenase 3 family member B2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 28.7), Lung (RPKM 15.5) and 9 other tissues See more
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Genomic context

See Aldh3b2 in Genome Data Viewer
Location:
1q43
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210679749..210694187)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (201250260..201264699)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219215023..219218488)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 3 family, member B3 Neighboring gene aldehyde dehydrogenase 3 family, member B3-like, pseudogene 1 Neighboring gene aldehyde dehydrogenase 3 family, member B2, pseudogene 1 Neighboring gene aldehyde dehydrogenase 3 family, member B2 like 1 Neighboring gene aminoacylase 3 Neighboring gene T-box transcription factor 10 Neighboring gene nudix hydrolase 8

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 3-chloroallyl aldehyde dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables aldehyde dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables aldehyde dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 
enables aldehyde dehydrogenase [NAD(P)+] activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in aldehyde metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in aldehyde metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
aldehyde dehydrogenase 3 family, member B2; aldehyde dehydrogenase family 3 member B2
Names
aldehyde dehydrogenase family 3 member B1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432597.1NP_001419526.1  aldehyde dehydrogenase 3 family, member B2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6AKN2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    210679749..210694187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101313.1XP_038957241.1  aldehyde dehydrogenase family 3 member B2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6AW67
    Related
    ENSRNOP00000112564.1, ENSRNOT00000143105.1
    Conserved Domains (1) summary
    cl11961
    Location:6397
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily
  2. XM_063279813.1XP_063135883.1  aldehyde dehydrogenase family 3 member B2 isoform X1

    Related
    ENSRNOP00000111545.1, ENSRNOT00000143646.1