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Ccdc137 coiled-coil domain containing 137 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688298, updated on 4-Jan-2025

Summary

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Official Symbol
Ccdc137provided by RGD
Official Full Name
coiled-coil domain containing 137provided by RGD
Primary source
RGD:1591129
See related
EnsemblRapid:ENSRNOG00000048712 AllianceGenome:RGD:1591129
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in chromosome and fibrillar center. Predicted to be active in nucleus. Orthologous to human CCDC137 (coiled-coil domain containing 137). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 50.5), Spleen (RPKM 42.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccdc137 in Genome Data Viewer
Location:
10q32.3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (106229099..106235502)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (105730776..105737158)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (109630099..109636480)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tetraspanin 10 Neighboring gene phosphodiesterase 6G Neighboring gene oxidoreductase-like domain containing 1 Neighboring gene ARF like GTPase 16 Neighboring gene hepatocyte growth factor-regulated tyrosine kinase substrate

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Ohta S, et al. Cell, 2010 Sep 3. PMID 20813266, Free PMC Article
  2. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome ISO
Inferred from Sequence Orthology
more info
  
located_in fibrillar center IEA
Inferred from Electronic Annotation
more info
  
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 137

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143896.1 → NP_001137368.1  coiled-coil domain-containing protein 137

    See identical proteins and their annotated locations for NP_001137368.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A0A8I6A5X5, A6HLD2, M0RAS3
    Related
    ENSRNOP00000066630.1, ENSRNOT00000072099.3
    Conserved Domains (1) summary
    PTZ00121
    Location:43 → 188
    PTZ00121; MAEBL; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    106229099..106235502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269872.1 → XP_063125942.1  coiled-coil domain-containing protein 137 isoform X1

  2. XM_063269873.1 → XP_063125943.1  coiled-coil domain-containing protein 137 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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