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Exoc3l2 exocyst complex component 3-like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 686809, updated on 27-Nov-2024

Summary

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Official Symbol
Exoc3l2provided by RGD
Official Full Name
exocyst complex component 3-like 2provided by RGD
Primary source
RGD:1592539
See related
EnsemblRapid:ENSRNOG00000017448 AllianceGenome:RGD:1592539
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in exocytosis. Predicted to act upstream of or within in utero embryonic development. Predicted to be part of exocyst. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 71.2), Testes (RPKM 45.4) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Exoc3l2 in Genome Data Viewer
Location:
1q21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88241784..88273352)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79113784..79145359)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80372708..80404275)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene creatine kinase, M-type Neighboring gene microtubule affinity regulating kinase 4 Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 3 Neighboring gene trafficking protein particle complex subunit 6A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice. Wilson R, et al. Wellcome Open Res, 2016. PMID 27996060, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in exocyst localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within in utero embryonic development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of exocyst IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
exocyst complex component 3-like 2; exocyst complex component 3-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432576.1 → NP_001419505.1  exocyst complex component 3-like 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6A4S8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    88241784..88273352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039100835.2 → XP_038956763.1  exocyst complex component 3-like protein 2

    Related
    ENSRNOP00000087641.1, ENSRNOT00000110706.2
    Conserved Domains (1) summary
    cl19885
    Location:214 → 721
    Sec6; Exocyst complex component Sec6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials