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Ccdc13 coiled-coil domain containing 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 686091, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc13provided by RGD
Official Full Name
coiled-coil domain containing 13provided by RGD
Primary source
RGD:1586605
See related
EnsemblRapid:ENSRNOG00000025643 AllianceGenome:RGD:1586605
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in cytoplasmic microtubule organization and non-motile cilium assembly. Predicted to act upstream of or within DNA damage response. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be active in centriolar satellite. Orthologous to human CCDC13 (coiled-coil domain containing 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 68.0), Muscle (RPKM 11.0) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccdc13 in Genome Data Viewer
Location:
8q32
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130335797..130391658, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121455202..121507487, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130436529..130475521, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene kelch-like family member 40 Neighboring gene hedgehog acyltransferase-like Neighboring gene HIG1 hypoxia inducible domain family, member 1A Neighboring gene atypical chemokine receptor 2 Neighboring gene cytochrome P450 family 8 subfamily B member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability. Staples CJ, et al. J Cell Sci, 2014 Jul 1. PMID 24816561
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic microtubule organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cytoplasmic microtubule organization ISO
Inferred from Sequence Orthology
more info
  
involved_in non-motile cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within non-motile cilium assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in centriolar satellite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain containing 13; coiled-coil domain-containing protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    130335797..130391658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039082754.2 → XP_038938682.1  coiled-coil domain-containing protein 13 isoform X2

    UniProtKB/TrEMBL
    A0A8I6AFB0
    Conserved Domains (2) summary
    COG1196
    Location:76 → 454
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:339 → 610
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_039082751.2 → XP_038938679.1  coiled-coil domain-containing protein 13 isoform X1

    UniProtKB/TrEMBL
    M0R4S7
    Conserved Domains (2) summary
    COG1196
    Location:76 → 455
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:340 → 611
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_063266488.1 → XP_063122558.1  coiled-coil domain-containing protein 13 isoform X2

    UniProtKB/TrEMBL
    A0A8I6AFB0

  4. XM_039082753.2 → XP_038938681.1  coiled-coil domain-containing protein 13 isoform X1

    UniProtKB/TrEMBL
    M0R4S7
    Related
    ENSRNOP00000093179.2, ENSRNOT00000100163.2
    Conserved Domains (2) summary
    COG1196
    Location:76 → 455
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:340 → 611
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  5. XM_039082755.2 → XP_038938683.1  coiled-coil domain-containing protein 13 isoform X3

    Conserved Domains (2) summary
    COG1196
    Location:76 → 455
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:340 → 611
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  6. XM_063266490.1 → XP_063122560.1  coiled-coil domain-containing protein 13 isoform X5

  7. XM_063266491.1 → XP_063122561.1  coiled-coil domain-containing protein 13 isoform X5

  8. XM_063266489.1 → XP_063122559.1  coiled-coil domain-containing protein 13 isoform X4

  9. XM_063266492.1 → XP_063122562.1  coiled-coil domain-containing protein 13 isoform X6

Nucleotide Protein Strain
Heading Accession and Version

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