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Mogat3 monoacylglycerol O-acyltransferase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685560, updated on 14-Nov-2024

Summary

Official Symbol
Mogat3provided by RGD
Official Full Name
monoacylglycerol O-acyltransferase 3provided by RGD
Primary source
RGD:1592588
See related
AllianceGenome:RGD:1592588
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable 2-acylglycerol O-acyltransferase activity and diacylglycerol O-acyltransferase activity. Predicted to be involved in diacylglycerol biosynthetic process; monoacylglycerol biosynthetic process; and triglyceride biosynthetic process. Predicted to be located in perinuclear endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to several human genes including DGAT2L7P (diacylglycerol O-acyltransferase 2 like 7, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 24.1) See more
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Genomic context

See Mogat3 in Genome Data Viewer
Location:
12q12
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (25305390..25307024, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (19668703..19669420, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22708622..22710787, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 1 subunit sigma 1 Neighboring gene VGF nerve growth factor inducible Neighboring gene procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 Neighboring gene microRNA 702 Neighboring gene zinc finger, HIT-type containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 2-acylglycerol O-acyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables diacylglycerol O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables diacylglycerol O-acyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in monoacylglycerol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in triglyceride biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in triglyceride biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P
Names
2-acylglycerol O-acyltransferase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    25305390..25307024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001064308.6XP_001064308.2  putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P

    Conserved Domains (1) summary
    cl17185
    Location:283
    LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis