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Rpl34 ribosomal protein L34 [ Mus musculus (house mouse) ]

Gene ID: 68436, updated on 27-Nov-2024

Summary

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Official Symbol
Rpl34provided by MGI
Official Full Name
ribosomal protein L34provided by MGI
Primary source
MGI:MGI:1915686
See related
Ensembl:ENSMUSG00000062006 AllianceGenome:MGI:1915686
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1100001I22Rik
Summary
A structural constituent of ribosome. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human RPL34 (ribosomal protein L34). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in large intestine adult (RPKM 318.4), placenta adult (RPKM 290.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rpl34 in Genome Data Viewer
Location:
3 G3; 3 60.55 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (130520476..130524047, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (130726827..130730398, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36373 Neighboring gene STARR-positive B cell enhancer ABC_E4590 Neighboring gene STARR-positive B cell enhancer ABC_E4591 Neighboring gene STARR-positive B cell enhancer ABC_E828 Neighboring gene oligosaccharyltransferase complex subunit (non-catalytic) Neighboring gene STARR-positive B cell enhancer ABC_E1266 Neighboring gene STARR-seq mESC enhancer starr_08989 Neighboring gene predicted gene 43522 Neighboring gene predicted gene, 36443

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins. Bayés A, et al. PLoS One, 2012. PMID 23071613, Free PMC Article
  2. Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Jiang X, et al. Nat Commun, 2023 Jun 22. PMID 37349316, Free PMC Article
  3. A male germ-cell-specific ribosome controls male fertility. Li H, et al. Nature, 2022 Dec. PMID 36517592
  4. In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Distler U, et al. Proteomics, 2014 Nov. PMID 25211037
  5. Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Kondrashov N, et al. Cell, 2011 Apr 29. PMID 21529712, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC103270

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion HDA PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
large ribosomal subunit protein eL34
Names
60S ribosomal protein L34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005859.4 → NP_001005859.1  large ribosomal subunit protein eL34

    See identical proteins and their annotated locations for NP_001005859.1

    Status: VALIDATED

    Source sequence(s)
    AC154993
    Consensus CDS
    CCDS17841.1
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9
    Related
    ENSMUSP00000078092.7, ENSMUST00000079085.11
    Conserved Domains (1) summary
    pfam01199
    Location:1 → 96
    Ribosomal_L34e; Ribosomal protein L34e

  2. NM_001287581.2 → NP_001274510.1  large ribosomal subunit protein eL34

    See identical proteins and their annotated locations for NP_001274510.1

    Status: VALIDATED

    Source sequence(s)
    AC154993
    Consensus CDS
    CCDS17841.1
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9
    Related
    ENSMUSP00000142486.2, ENSMUST00000196202.5
    Conserved Domains (1) summary
    pfam01199
    Location:1 → 96
    Ribosomal_L34e; Ribosomal protein L34e

  3. NM_001429093.1 → NP_001416022.1  large ribosomal subunit protein eL34

    Status: VALIDATED

    Source sequence(s)
    AC154993
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9

  4. NM_001429094.1 → NP_001416023.1  large ribosomal subunit protein eL34

    Status: VALIDATED

    Source sequence(s)
    AC154993
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9

  5. NM_001429095.1 → NP_001416024.1  large ribosomal subunit protein eL34

    Status: VALIDATED

    Source sequence(s)
    AC154993
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9

  6. NM_001429096.1 → NP_001416025.1  large ribosomal subunit protein eL34

    Status: VALIDATED

    Source sequence(s)
    AC154993
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9

  7. NM_026724.3 → NP_081000.1  large ribosomal subunit protein eL34

    See identical proteins and their annotated locations for NP_081000.1

    Status: VALIDATED

    Source sequence(s)
    AC154993
    Consensus CDS
    CCDS17841.1
    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9
    Related
    ENSMUSP00000086614.5, ENSMUST00000062601.14
    Conserved Domains (1) summary
    pfam01199
    Location:1 → 96
    Ribosomal_L34e; Ribosomal protein L34e

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    130520476..130524047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163263.1 → XP_036019156.1  large ribosomal subunit protein eL34 isoform X1

    UniProtKB/Swiss-Prot
    Q497V4, Q9D1R9
    Conserved Domains (1) summary
    pfam01199
    Location:1 → 96
    Ribosomal_L34e; Ribosomal protein L34e
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D1R9.2 GenPept UniProtKB/Swiss-Prot:Q9D1R9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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