Tlcd1 TLC domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tlcd1provided by MGI
Official Full Name: TLC domain containing 1provided by MGI
Primary source: MGI:MGI:1915572
See related: Ensembl:ENSMUSG00000019437 AllianceGenome:MGI:1915572
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Predicted to be active in plasma membrane. Orthologous to human TLCD1 (TLC domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in adrenal adult (RPKM 31.4), mammary gland adult (RPKM 18.8) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 B5; 11 46.74 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (78068956..78071646)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (78176716..78181019)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AU015616 (e-PCR)
- UniSTS:208709

AA690150 (e-PCR)
- UniSTS:160127

RH124848 (e-PCR)
- UniSTS:161670

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in membrane assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in membrane assembly	IEA Inferred from Electronic Annotation more info
involved_in membrane assembly	ISO Inferred from Sequence Orthology more info
involved_in phospholipid homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid homeostasis	IEA Inferred from Electronic Annotation more info
involved_in phospholipid homeostasis	ISO Inferred from Sequence Orthology more info
involved_in plasma membrane organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in plasma membrane organization	IEA Inferred from Electronic Annotation more info
involved_in plasma membrane organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of membrane lipid distribution	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of membrane lipid distribution	IEA Inferred from Electronic Annotation more info
involved_in regulation of membrane lipid distribution	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: TLC domain-containing protein 1

Names: calfacilitin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.