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Cmc1 C-X9-C motif containing 1 [ Mus musculus (house mouse) ]

Gene ID: 67899, updated on 27-Nov-2024

Summary

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Official Symbol
Cmc1provided by MGI
Official Full Name
C-X9-C motif containing 1provided by MGI
Primary source
MGI:MGI:1915149
See related
Ensembl:ENSMUSG00000039163 AllianceGenome:MGI:1915149
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010110K16Rik; 2010312P05Rik
Summary
Predicted to enable metal ion binding activity. Located in mitochondrion. Orthologous to human CMC1 (C-X9-C motif containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in cerebellum adult (RPKM 5.5), bladder adult (RPKM 5.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Cmc1 in Genome Data Viewer
Location:
9 F3; 9 69.87 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (117893051..117979264, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (118063983..118150196, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RNA binding motif, single stranded interacting protein Neighboring gene predicted gene, 26614 Neighboring gene STARR-seq mESC enhancer starr_25450 Neighboring gene predicted gene, 50606 Neighboring gene STARR-positive B cell enhancer ABC_E3864 Neighboring gene STARR-positive B cell enhancer ABC_E2921 Neighboring gene STARR-positive B cell enhancer mm9_chr9:117962449-117962749 Neighboring gene zinc finger, CW type with PWWP domain 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:118059288-118059397 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:118105829-118106030 Neighboring gene 5-azacytidine induced gene 2 Neighboring gene predicted gene, 17399 Neighboring gene predicted gene, 53195

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo. O'Brien R, et al. J Biol Chem, 2015 Jul 31. PMID 26025364, Free PMC Article
  2. Huntingtin interacting proteins are genetic modifiers of neurodegeneration. Kaltenbach LS, et al. PLoS Genet, 2007 May 11. PMID 17500595, Free PMC Article
  3. The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes. Liu F, et al. Mol Cell Proteomics, 2018 Feb. PMID 29222160, Free PMC Article
  4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  5. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
COX assembly mitochondrial protein homolog
Names
COX assembly mitochondrial protein 1
cmc1p

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026442.3 → NP_080718.1  COX assembly mitochondrial protein homolog

    See identical proteins and their annotated locations for NP_080718.1

    Status: VALIDATED

    Source sequence(s)
    AC157475, AK020626, CJ170455
    Consensus CDS
    CCDS40800.1
    UniProtKB/Swiss-Prot
    Q6PH95, Q80ZR0, Q9CPZ8
    Related
    ENSMUSP00000047904.10, ENSMUST00000044220.11
    Conserved Domains (1) summary
    pfam08583
    Location:19 → 87
    Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    117893051..117979264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155219.1 → XP_036011112.1  COX assembly mitochondrial protein homolog isoform X1

    Conserved Domains (1) summary
    pfam08583
    Location:15 → 83
    Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like

  2. XM_011242996.4 → XP_011241298.1  COX assembly mitochondrial protein homolog isoform X1

    Conserved Domains (1) summary
    pfam08583
    Location:15 → 83
    Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CPZ8.1 GenPept UniProtKB/Swiss-Prot:Q9CPZ8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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