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Susd6 sushi domain containing 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 678893, updated on 27-Nov-2024

Summary

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Official Symbol
Susd6provided by RGD
Official Full Name
sushi domain containing 6provided by RGD
Primary source
RGD:1595528
See related
EnsemblRapid:ENSRNOG00000045941 AllianceGenome:RGD:1595528
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in DNA damage response. Orthologous to human SUSD6 (sushi domain containing 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 89.0), Spleen (RPKM 78.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Susd6 in Genome Data Viewer
Location:
6q24
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (106130183..106262900)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (100437834..100531621)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (104437104..104532522)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479447 Neighboring gene solute carrier family 39, member 9 Neighboring gene pleckstrin homology and coiled-coil domain containing D1 Neighboring gene coiled-coil domain containing 177 Neighboring gene serine and arginine rich splicing factor 5 Neighboring gene solute carrier family 10 member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected]. Polato F, et al. J Natl Cancer Inst, 2014 Apr. PMID 24652652, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in DNA damage response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA damage response ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
sushi domain-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398930.2 → NP_001385859.1  sushi domain-containing protein 6 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A096MK85, A6JDK3
    Related
    ENSRNOP00000068418.1, ENSRNOT00000076485.4
    Conserved Domains (1) summary
    cd00033
    Location:42 → 98
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  2. NM_001428965.1 → NP_001415894.1  sushi domain-containing protein 6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6JDK2, M0R5N9

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    106130183..106262900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262461.1 → XP_063118531.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9

  2. XM_063262462.1 → XP_063118532.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9

  3. XM_039113294.2 → XP_038969222.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  4. XM_039113295.2 → XP_038969223.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  5. XM_039113292.2 → XP_038969220.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  6. XM_063262465.1 → XP_063118535.1  sushi domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A096MK85, A6JDK3

  7. XM_039113293.2 → XP_038969221.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  8. XM_063262463.1 → XP_063118533.1  sushi domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A096MK85, A6JDK3

  9. XM_039113291.2 → XP_038969219.1  sushi domain-containing protein 6 isoform X1

    Related
    ENSRNOP00000064712.2, ENSRNOT00000070995.5
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  10. XM_039113296.2 → XP_038969224.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  11. XM_039113297.2 → XP_038969225.1  sushi domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A6JDK2, M0R5N9
    Conserved Domains (1) summary
    cd00033
    Location:63 → 119
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

  12. XM_063262464.1 → XP_063118534.1  sushi domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A096MK85, A6JDK3
Nucleotide Protein Strain
Heading Accession and Version

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