rab40c RAB40c, member RAS oncogene family [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rab40cprovided by ZNC
Official Full Name: RAB40c, member RAS oncogene familyprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030515-1
See related: Ensembl:ENSDARG00000061208 AllianceGenome:ZFIN:ZDB-GENE-030515-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb453; wu:fk50d06; zgc:136966
Summary: Predicted to enable GTPase activity. Predicted to be involved in exocytosis. Predicted to act upstream of or within intracellular signal transduction. Predicted to be active in endosome; plasma membrane; and synaptic vesicle. Is expressed in central nervous system; cranial ganglion; forebrain; and retina. Orthologous to human RAB40C (RAB40C, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (26751861..26787196, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (26620990..26656325, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fk50d06.x1 (e-PCR)
- UniSTS:201090

fi86b10.y1 (e-PCR)
- UniSTS:198123

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synaptic vesicle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ras-related protein Rab-40C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001040348.1 → NP_001035438.1 ras-related protein Rab-40C

See identical proteins and their annotated locations for NP_001035438.1

Status: PROVISIONAL

Source sequence(s)

BC115347

UniProtKB/TrEMBL

A0A8M1N8T2, Q1RLP4

Related

ENSDARP00000081481.4, ENSDART00000087047.5

Conserved Domains (2) summary

cd04121
Location:9 → 279

Rab40; Rab GTPase family 40 (Rab40) contains Rab40a, Rab40b and Rab40c

cd03742
Location:187 → 229

SOCS_Rab40; SOCS (suppressors of cytokine signaling) box of Rab40-like proteins. Rab40 is part of the Rab family of small GTP-binding proteins that form the largest family within the Ras superfamily. Rab proteins regulate vesicular trafficking pathways, behaving as ...