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Macroh2a3 macroH2A.3 histone [ Mus musculus (house mouse) ]

Gene ID: 67552, updated on 4-Jan-2025

Summary

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Official Symbol
Macroh2a3provided by MGI
Official Full Name
macroH2A.3 histoneprovided by MGI
Primary source
MGI:MGI:1914802
See related
AllianceGenome:MGI:1914802
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2afy3; 4933432H23Rik
Summary
Is expressed in early tubule; female associated reproductive structure; and male associated reproductive structure. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Macroh2a3 in Genome Data Viewer
Location:
15 D1; 15 26.42 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (62089390..62091300, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (62217541..62219451, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_38818 Neighboring gene STARR-seq mESC enhancer starr_38819 Neighboring gene STARR-seq mESC enhancer starr_38820 Neighboring gene myelocytomatosis oncogene Neighboring gene STARR-seq mESC enhancer starr_38824 Neighboring gene Pvt1 oncogene Neighboring gene predicted gene, 53890 Neighboring gene STARR-positive B cell enhancer ABC_E5482 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:62001280-62001493 Neighboring gene STARR-positive B cell enhancer ABC_E7373 Neighboring gene STARR-positive B cell enhancer mm9_chr15:62013150-62013450 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:62044000-62044201 Neighboring gene STARR-seq mESC enhancer starr_38830 Neighboring gene STARR-positive B cell enhancer mm9_chr15:62189952-62190252 Neighboring gene STARR-seq mESC enhancer starr_38831 Neighboring gene STARR-seq mESC enhancer starr_38832 Neighboring gene STARR-seq mESC enhancer starr_38833 Neighboring gene STARR-seq mESC enhancer starr_38834 Neighboring gene predicted gene, 41333 Neighboring gene STARR-seq mESC enhancer starr_38835 Neighboring gene predicted gene, 22521

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping. Filipescu D, et al. Nat Cell Biol, 2023 Sep. PMID 37605008, Free PMC Article
  2. Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant. Chadwick BP, et al. Hum Mol Genet, 2001 May 1. PMID 11331621
  3. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.
    Title: MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • H2A histone family, member Y3
  • macroH2A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003523.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC133090

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    62089390..62091300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_026230.2: Suppressed sequence

    Description
    NM_026230.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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