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Sec14l5 SEC14-like lipid binding 5 [ Mus musculus (house mouse) ]

Gene ID: 665119, updated on 27-Nov-2024

Summary

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Official Symbol
Sec14l5provided by MGI
Official Full Name
SEC14-like lipid binding 5provided by MGI
Primary source
MGI:MGI:3616084
See related
Ensembl:ENSMUSG00000091712 AllianceGenome:MGI:3616084
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be active in cytoplasm. Is expressed in brain. Orthologous to human SEC14L5 (SEC14 like lipid binding 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in cerebellum adult (RPKM 6.0), cortex adult (RPKM 3.5) and 9 other tissues See more
Orthologs
human all
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Genomic context

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See Sec14l5 in Genome Data Viewer
Location:
16 A1; 16 2.5 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (4964758..5005135)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (5146906..5187271)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene ubinuclein 1 Neighboring gene predicted gene, 23483 Neighboring gene transmembrane protein 126A pseudogene Neighboring gene periplakin Neighboring gene N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Neighboring gene expressed sequence AU021092 Neighboring gene microRNA 6364

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Quintens R, et al. Biol Open, 2015 Feb 13. PMID 25681390, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SEC14-like protein 5
Names
SEC14-like 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127725.2 → NP_001121197.1  SEC14-like protein 5 isoform 1

    See identical proteins and their annotated locations for NP_001121197.1

    Status: VALIDATED

    Source sequence(s)
    AC124576
    Consensus CDS
    CCDS49752.1
    UniProtKB/TrEMBL
    B2RXM5
    Related
    ENSMUSP00000128063.2, ENSMUST00000165810.2
    Conserved Domains (3) summary
    smart00516
    Location:306 → 479
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    smart01100
    Location:243 → 288
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam04707
    Location:17 → 173
    PRELI; PRELI-like family

  2. NM_001417648.1 → NP_001404577.1  SEC14-like protein 5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC124576
    UniProtKB/TrEMBL
    B2RXM5
    Related
    ENSMUSP00000155164.2, ENSMUST00000230616.2

  3. NM_001417649.1 → NP_001404578.1  SEC14-like protein 5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC124576
    UniProtKB/TrEMBL
    B2RXM5

  4. NM_001417650.1 → NP_001404579.1  SEC14-like protein 5 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC124576

  5. NM_001417651.1 → NP_001404580.1  SEC14-like protein 5 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC124576

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    4964758..5005135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522466.5 → XP_006522529.1  SEC14-like protein 5 isoform X3

    Conserved Domains (4) summary
    smart00516
    Location:306 → 436
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    smart01100
    Location:243 → 288
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam04707
    Location:17 → 173
    PRELI; PRELI-like family
    cl18951
    Location:179 → 309
    Amidase

RNA

  1. XR_001781850.3 RNA Sequence

  2. XR_384588.5 RNA Sequence

  3. XR_004939205.1 RNA Sequence

  4. XR_004939207.1 RNA Sequence

  5. XR_384587.5 RNA Sequence

  6. XR_004939208.1 RNA Sequence

  7. XR_004939206.1 RNA Sequence

  8. XR_004939204.1 RNA Sequence

  9. XR_001781851.3 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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