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TCOF1 treacle ribosome biogenesis factor 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 664735, updated on 17-Aug-2024

Summary

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Official Symbol
TCOF1provided by VGNC
Official Full Name
treacle ribosome biogenesis factor 1provided by VGNC
Primary source
VGNC:VGNC:78294
See related
Ensembl:ENSMMUG00000009111
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See TCOF1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
28
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (147870477..147910470)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (148491388..148531300)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent protein kinase II alpha Neighboring gene arylsulfatase family member I Neighboring gene CD74 molecule Neighboring gene ribosomal protein S14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reduced TCOF1 mRNA level in a rhesus macaque with Treacher Collins-like syndrome: further evidence for haploinsufficiency of treacle as the cause of disease. Shows KH, et al. Mamm Genome, 2006 Feb. PMID 16465596
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
treacle protein
Names
Treacher Collins-Franceschetti syndrome 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039952.1 → NP_001035041.1  treacle protein

    Status: PROVISIONAL

    Source sequence(s)
    DQ085095, DQ085096
    UniProtKB/TrEMBL
    A0A1D5RKQ9
    Related
    ENSMMUP00000060903.2, ENSMMUT00000077515.2
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:388 → 913
    Treacle; Treacher Collins syndrome protein Treacle

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    147870477..147910470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015141160.2 → XP_014996646.2  treacle protein isoform X1

    UniProtKB/TrEMBL
    A0A1D5QVN6, A0A1D5RKQ9
    Related
    ENSMMUP00000052116.2, ENSMMUT00000068743.2
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:388 → 902
    Treacle; Treacher Collins syndrome protein Treacle

  2. XM_015141162.2 → XP_014996648.2  treacle protein isoform X3

    UniProtKB/TrEMBL
    A0A1D5R7L3, A0A1D5RKQ9
    Related
    ENSMMUP00000056302.2, ENSMMUT00000056185.2
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:388 → 902
    Treacle; Treacher Collins syndrome protein Treacle

  3. XM_015141164.2 → XP_014996650.2  treacle protein isoform X5

    UniProtKB/TrEMBL
    A0A1D5RKQ9
    Related
    ENSMMUP00000075119.1, ENSMMUT00000087052.1
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:388 → 902
    Treacle; Treacher Collins syndrome protein Treacle

  4. XM_015141161.2 → XP_014996647.2  treacle protein isoform X2

    UniProtKB/TrEMBL
    A0A1D5R7L3
    Conserved Domains (3) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    PHA03247
    Location:798 → 1143
    PHA03247; large tegument protein UL36; Provisional
    pfam03546
    Location:388 → 902
    Treacle; Treacher Collins syndrome protein Treacle

  5. XM_028849026.1 → XP_028704859.1  treacle protein isoform X4

    UniProtKB/TrEMBL
    A0A1D5RKQ9
    Conserved Domains (3) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    PHA03247
    Location:798 → 1240
    PHA03247; large tegument protein UL36; Provisional
    pfam03546
    Location:388 → 902
    Treacle; Treacher Collins syndrome protein Treacle

  6. XM_028849027.1 → XP_028704860.1  treacle protein isoform X6

    UniProtKB/TrEMBL
    A0A1D5R7L3
    Related
    ENSMMUP00000011956.4, ENSMMUT00000012749.4
    Conserved Domains (3) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    PHA03247
    Location:792 → 1212
    PHA03247; large tegument protein UL36; Provisional
    pfam03546
    Location:388 → 862
    Treacle; Treacher Collins syndrome protein Treacle

RNA

  1. XR_003730062.1 RNA Sequence

  2. XR_003730063.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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