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Eid3 EP300 interacting inhibitor of differentiation 3 [ Mus musculus (house mouse) ]

Gene ID: 66341, updated on 4-Jan-2025

Summary

Official Symbol
Eid3provided by MGI
Official Full Name
EP300 interacting inhibitor of differentiation 3provided by MGI
Primary source
MGI:MGI:1913591
See related
Ensembl:ENSMUSG00000109864 AllianceGenome:MGI:1913591
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NS4EB; 1700027M21Rik
Summary
Predicted to be involved in DNA repair. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Orthologous to human EID3 (EP300 interacting inhibitor of differentiation 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Eid3 in Genome Data Viewer
Location:
10 C1; 10 40.66 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (82702460..82703764)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (82866626..82867930)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700028I16 gene Neighboring gene STARR-seq mESC enhancer starr_27376 Neighboring gene STARR-positive B cell enhancer ABC_E9798 Neighboring gene STARR-seq mESC enhancer starr_27377 Neighboring gene thioredoxin reductase 1 Neighboring gene predicted gene, 38560 Neighboring gene STARR-seq mESC enhancer starr_27378 Neighboring gene STARR-positive B cell enhancer ABC_E3903 Neighboring gene STARR-positive B cell enhancer ABC_E5161 Neighboring gene STARR-positive B cell enhancer ABC_E10633 Neighboring gene predicted gene, 33781 Neighboring gene predicted gene 4799

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC118226

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Smc5-Smc6 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Smc5-Smc6 complex ISO
Inferred from Sequence Orthology
more info
 
part_of Smc5-Smc6 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
EP300-interacting inhibitor of differentiation 3
Names
EID-1-like inhibitor of differentiation 3
non-SMC element 4 homolog B
non-structural maintenance of chromosomes element 4 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025499.2NP_079775.2  EP300-interacting inhibitor of differentiation 3

    See identical proteins and their annotated locations for NP_079775.2

    Status: VALIDATED

    Source sequence(s)
    BC099545, CJ046810
    Consensus CDS
    CCDS83739.1
    UniProtKB/Swiss-Prot
    Q3TTL4, Q3V124, Q4KL03, Q8CF34, Q9CVN8
    Related
    ENSMUSP00000147261.2, ENSMUST00000211623.2
    Conserved Domains (2) summary
    pfam08743
    Location:283371
    Nse4_C; Nse4 C-terminal
    pfam15412
    Location:132178
    Nse4-Nse3_bdg; Binding domain of Nse4/EID3 to Nse3-MAGE

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    82702460..82703764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)