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Hsbp1l1 heat shock factor binding protein 1-like 1 [ Mus musculus (house mouse) ]

Gene ID: 66255, updated on 27-Nov-2024

Summary

Official Symbol
Hsbp1l1provided by MGI
Official Full Name
heat shock factor binding protein 1-like 1provided by MGI
Primary source
MGI:MGI:1913505
See related
Ensembl:ENSMUSG00000078963 AllianceGenome:MGI:1913505
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810005K13Rik
Summary
Predicted to enable transcription corepressor activity. Predicted to be involved in cellular heat acclimation. Predicted to be active in cytosol and nucleus. Orthologous to human HSBP1L1 (heat shock factor binding protein 1 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in testis adult (RPKM 1.4), kidney adult (RPKM 0.6) and 18 other tissues See more
Orthologs
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Genomic context

See Hsbp1l1 in Genome Data Viewer
Location:
18 E3; 18 53.35 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (80272154..80293329, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (80228939..80250102, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5666 Neighboring gene ribosome binding factor A, opposite strand Neighboring gene ribosome binding factor A Neighboring gene thioredoxin-like 4A Neighboring gene N(alpha)-acetyltransferase 12, NatA catalytic subunit Neighboring gene STARR-seq mESC enhancer starr_45175 Neighboring gene solute carrier family 66 member 2 Neighboring gene potassium voltage-gated channel, subfamily G, member 2 Neighboring gene predicted gene, 26676

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular heat acclimation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
heat shock factor-binding protein 1-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136181.1NP_001129653.1  heat shock factor-binding protein 1-like protein 1

    See identical proteins and their annotated locations for NP_001129653.1

    Status: VALIDATED

    Source sequence(s)
    AC131065, AK141935, BC151118
    Consensus CDS
    CCDS50333.1
    UniProtKB/Swiss-Prot
    B2RXB2
    Related
    ENSMUSP00000132852.2, ENSMUST00000166219.2
    Conserved Domains (1) summary
    pfam06825
    Location:1462
    HSBP1; Heat shock factor binding protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    80272154..80293329 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526518.5XP_006526581.1  heat shock factor-binding protein 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006526581.1

    UniProtKB/Swiss-Prot
    B2RXB2
    Conserved Domains (1) summary
    pfam06825
    Location:1462
    HSBP1; Heat shock factor binding protein 1
  2. XM_006526517.5XP_006526580.1  heat shock factor-binding protein 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006526580.1

    UniProtKB/Swiss-Prot
    B2RXB2
    Related
    ENSMUSP00000158095.2, ENSMUST00000237192.2
    Conserved Domains (1) summary
    pfam06825
    Location:1462
    HSBP1; Heat shock factor binding protein 1