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DPP4 dipeptidyl peptidase 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 654491, updated on 17-Aug-2024

Summary

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Official Symbol
DPP4provided by VGNC
Official Full Name
dipeptidyl peptidase 4provided by VGNC
Primary source
VGNC:VGNC:71979
See related
Ensembl:ENSMMUG00000008387
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DPP4 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
27
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (49061121..49145325, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (48722453..48807125, complement)

Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene T-box brain transcription factor 1 Neighboring gene solute carrier family 4 member 10 Neighboring gene small nucleolar RNA U13 Neighboring gene glucagon Neighboring gene fibroblast activation protein alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4. van Doremalen N, et al. J Virol, 2014 Aug. PMID 24899185, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dipeptidyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dipeptidyl peptidase 4
Names
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)
dipeptidylpeptidase 4
dipeptidylpeptidase IV
NP_001034279.2
XP_014965616.1
XP_014965617.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039190.2 → NP_001034279.2  dipeptidyl peptidase 4

    See identical proteins and their annotated locations for NP_001034279.2

    Status: VALIDATED

    Source sequence(s)
    JU474559
    UniProtKB/TrEMBL
    F6VRB0, G7N865
    Related
    ENSMMUP00000011001.2, ENSMMUT00000011731.4
    Conserved Domains (2) summary
    pfam00326
    Location:559 → 763
    Peptidase_S9; Prolyl oligopeptidase family
    pfam00930
    Location:108 → 478
    DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041765.1 Reference Mmul_10 Primary Assembly

    Range
    49061121..49145325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015110130.2 → XP_014965616.1  dipeptidyl peptidase 4 isoform X1

    UniProtKB/TrEMBL
    G7N865
    Related
    ENSMMUP00000077781.1, ENSMMUT00000106855.1
    Conserved Domains (2) summary
    pfam00326
    Location:558 → 762
    Peptidase_S9; Prolyl oligopeptidase family
    pfam00930
    Location:107 → 477
    DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region

  2. XM_015110131.2 → XP_014965617.1  dipeptidyl peptidase 4 isoform X2

    UniProtKB/TrEMBL
    A0A5F8AIP8
    Conserved Domains (3) summary
    COG1506
    Location:314 → 680
    DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
    pfam00326
    Location:475 → 679
    Peptidase_S9; Prolyl oligopeptidase family
    pfam00930
    Location:24 → 394
    DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region
Nucleotide Protein
Heading Accession and Version

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