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GAGE12G G antigen 12G [ Homo sapiens (human) ]

Gene ID: 645073, updated on 27-Nov-2024

Summary

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Official Symbol
GAGE12Gprovided by HGNC
Official Full Name
G antigen 12Gprovided by HGNC
Primary source
HGNC:HGNC:31907
See related
Ensembl:ENSG00000215269 MIM:300731; AllianceGenome:HGNC:31907
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AL4; CT4.7; GAGE-12G
Expression
Restricted expression toward testis (RPKM 163.8) See more
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Genomic context

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See GAGE12G in Genome Data Viewer
Location:
Xp11.23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (49570397..49577757)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48886258..48893621)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (49335000..49342360)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene G antigen 12E Neighboring gene G antigen 12F Neighboring gene G antigen 12H Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:49354271-49354992 Neighboring gene G antigen 2A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220. Hou P, et al. Cancer Res, 2017 Aug 15. PMID 28625976, Free PMC Article
  2. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article
  3. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Huttlin EL, et al. Cell, 2021 May 27. PMID 33961781, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC132611

General protein information

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Preferred Names
G antigen 12G
Names
G antigen 12F/G/I
G antigen 12I
cancer/testis antigen 4.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098409.4 → NP_001091879.1  G antigen 12G isoform 1

    See identical proteins and their annotated locations for NP_001091879.1

    Status: VALIDATED

    Source sequence(s)
    AC142497
    Consensus CDS
    CCDS43947.1
    UniProtKB/Swiss-Prot
    B7ZM13, O76087, P0CL80, P0CL81, P0CL82, Q4V324, Q66I50
    UniProtKB/TrEMBL
    B7ZVY3
    Related
    ENSP00000416249.1, ENST00000445148.2
    Conserved Domains (1) summary
    pfam05831
    Location:1 → 111
    GAGE; GAGE protein

  2. NM_001354422.1 → NP_001341351.1  G antigen 12G isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC142497
    Conserved Domains (1) summary
    pfam05831
    Location:1 → 69
    GAGE; GAGE protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    49570397..49577757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    48886258..48893621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CL81.1 GenPept UniProtKB/Swiss-Prot:P0CL81

Gene LinkOut

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