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SMIM10L2B small integral membrane protein 10 like 2B [ Homo sapiens (human) ]

Gene ID: 644596, updated on 27-Nov-2024

Summary

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Official Symbol
SMIM10L2Bprovided by HGNC
Official Full Name
small integral membrane protein 10 like 2Bprovided by HGNC
Primary source
HGNC:HGNC:34500
See related
Ensembl:ENSG00000196972 AllianceGenome:HGNC:34500
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LINC00086; LINC00087; SMIM10L2A; NCRNA00086; NCRNA00087
Expression
Broad expression in brain (RPKM 9.9), heart (RPKM 4.0) and 14 other tissues See more
Orthologs
all
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Genomic context

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See SMIM10L2B in Genome Data Viewer
Location:
Xq26.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (135094985..135098712, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (133420353..133424080, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (134229015..134232742, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:134184927-134185713 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29979 Neighboring gene retrotransposon Gag like 8A Neighboring gene nucleolin pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21018 Neighboring gene Sharpr-MPRA regulatory region 8062 Neighboring gene SMIM10L2B antisense RNA 1 Neighboring gene embryonic testis differentiation homolog B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article
  2. VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Yue Y, et al. Cell Discov, 2018. PMID 29507755, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • FLJ41308, RP11-85L21.2

General protein information

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Preferred Names
small integral membrane protein 10-like protein 2B
Names
Small integral membrane protein 10-like protein 2A
long intergenic non-protein coding RNA 87

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348255.2 → NP_001335184.1  small integral membrane protein 10-like protein 2B

    Status: VALIDATED

    Source sequence(s)
    AL590325
    Consensus CDS
    CCDS87780.1
    UniProtKB/Swiss-Prot
    P0DMW4, P0DMW5
    Related
    ENSP00000487709.1, ENST00000433425.4
    Conserved Domains (1) summary
    pfam15118
    Location:21 → 77
    DUF4560; Domain of unknown function (DUF4560)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    135094985..135098712 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    133420353..133424080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DMW5.1 GenPept UniProtKB/Swiss-Prot:P0DMW5

Gene LinkOut

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Molecular Biology Databases
Research Materials