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ifi27.2 interferon alpha inducible protein 27.2 [ Danio rerio (zebrafish) ]

Gene ID: 641326, updated on 4-Jan-2025

Summary

Official Symbol
ifi27.2provided by ZNC
Official Full Name
interferon alpha inducible protein 27.2provided by ZNC
Primary source
ZFIN:ZDB-GENE-060901-4
See related
Ensembl:ENSDARG00000039243 AllianceGenome:ZFIN:ZDB-GENE-060901-4
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ifi27; isg12-2; isg12.1; isg12.2; zgc:123067; zgc:152791; zgc:158560
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in intrinsic apoptotic signaling pathway and release of cytochrome c from mitochondria. Predicted to be located in membrane. Predicted to be active in mitochondrial membrane. Orthologous to several human genes including IFI27 (interferon alpha inducible protein 27). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See ifi27.2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (37617515..37620290, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (37491625..37494400, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene interferon alpha inducible protein 27.1 Neighboring gene interferon alpha inducible protein 27.3 Neighboring gene interferon alpha inducible protein 27.4 Neighboring gene uncharacterized LOC101885881

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC123067, MGC152791, MGC158560

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in intrinsic apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in release of cytochrome c from mitochondria IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrial membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
interferon alpha inducible protein 27.2
Names
interferon stimulated gene 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007133.3NP_001007134.2  interferon alpha inducible protein 27.2

    See identical proteins and their annotated locations for NP_001007134.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    DY573454, EB984692
    UniProtKB/TrEMBL
    A0A8M1P1C3, F6NVZ1
    Related
    ENSDARP00000011827.7, ENSDART00000018064.9
    Conserved Domains (1) summary
    pfam06140
    Location:2489
    Ifi-6-16; Interferon-induced 6-16 family
  2. NM_001291934.1NP_001278863.1  interferon alpha inducible protein 27.2

    See identical proteins and their annotated locations for NP_001278863.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    DY573454, EB984692
    UniProtKB/TrEMBL
    A0A8M1P1C3, F6NVZ1
    Related
    ENSDARP00000147083.1, ENSDART00000193270.1
    Conserved Domains (1) summary
    pfam06140
    Location:2489
    Ifi-6-16; Interferon-induced 6-16 family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    37617515..37620290 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)