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nubp2 nucleotide binding protein 2 (MinD homolog, E. coli) [ Danio rerio (zebrafish) ]

Gene ID: 641290, updated on 9-Dec-2024

Summary

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Official Symbol
nubp2provided by ZNC
Official Full Name
nucleotide binding protein 2 (MinD homolog, E. coli)provided by ZNC
Primary source
ZFIN:ZDB-GENE-051023-10
See related
Ensembl:ENSDARG00000055653 AllianceGenome:ZFIN:ZDB-GENE-051023-10
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:123336
Summary
Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See nubp2 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (39178360..39186185, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (39286373..39294198, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 24 Neighboring gene ATPase H+ transporting V0 subunit cb Neighboring gene splA/ryanodine receptor domain and SOCS box containing 3b Neighboring gene uncharacterized LOC110438367

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC123336

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent FeS chaperone activity IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in iron-sulfur cluster assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within iron-sulfur cluster assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in iron-sulfur cluster assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cytosolic Fe-S cluster assembly factor nubp2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037114.2 → NP_001032191.2  cytosolic Fe-S cluster assembly factor nubp2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    EH446733, EH482962, EH542357
    UniProtKB/Swiss-Prot
    Q3B7Q7
    UniProtKB/TrEMBL
    A0A8M1N7W1, F1REW2
    Related
    ENSDARP00000112190.1, ENSDART00000123019.3
    Conserved Domains (2) summary
    TIGR01969
    Location:15 → 263
    minD_arch; cell division ATPase MinD, archaeal
    pfam10609
    Location:11 → 264
    ParA; NUBPL iron-transfer P-loop NTPase

  2. NM_001312901.1 → NP_001299830.1  cytosolic Fe-S cluster assembly factor nubp2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    CU929145
    UniProtKB/Swiss-Prot
    Q3B7Q7
    UniProtKB/TrEMBL
    A0A2R8Q6P8, A0A8M1P811
    Related
    ENSDARP00000148775.1, ENSDART00000191114.1
    Conserved Domains (2) summary
    COG0489
    Location:4 → 190
    Mrp; Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster [Cell cycle control, cell division, chromosome partitioning]
    pfam10609
    Location:2 → 223
    ParA; NUBPL iron-transfer P-loop NTPase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    39178360..39186185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3B7Q7.1 GenPept UniProtKB/Swiss-Prot:Q3B7Q7

Gene LinkOut

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