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Vmn2r117 vomeronasal 2, receptor 117 [ Mus musculus (house mouse) ]

Gene ID: 619788, updated on 9-Dec-2024

Summary

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Official Symbol
Vmn2r117provided by MGI
Official Full Name
vomeronasal 2, receptor 117provided by MGI
Primary source
MGI:MGI:3648766
See related
Ensembl:ENSMUSG00000091407 AllianceGenome:MGI:3648766
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
V2Rp6; EG619788
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Vmn2r117 in Genome Data Viewer
Location:
17 A3.3; 17 11.56 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23678649..23698571, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23459675..23479597, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 116 Neighboring gene vomeronasal 2, receptor, pseudogene 134 Neighboring gene olfactory receptor family 14 subfamily C member 47, peudogene 1 Neighboring gene STARR-seq mESC enhancer starr_42047 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit G1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sexual rejection via a vomeronasal receptor-triggered limbic circuit. Osakada T, et al. Nat Commun, 2018 Oct 26. PMID 30367054, Free PMC Article
  2. The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor. Haga S, et al. Nature, 2010 Jul 1. PMID 20596023
  3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal receptor Vmn2r117
Names
vomeronasal 2 receptor p6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104581.1 → NP_001098051.1  vomeronasal receptor Vmn2r117 precursor

    See identical proteins and their annotated locations for NP_001098051.1

    Status: INFERRED

    Source sequence(s)
    CT485617
    Consensus CDS
    CCDS50010.1
    UniProtKB/TrEMBL
    D7URW6, K7N6V1
    Related
    ENSMUSP00000126885.2, ENSMUST00000171996.3
    Conserved Domains (4) summary
    cd06365
    Location:41 → 504
    PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam00003
    Location:599 → 832
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:75 → 471
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:513 → 564
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    23678649..23698571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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