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EGFR epidermal growth factor receptor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 613027, updated on 17-Aug-2024

Summary

Official Symbol
EGFRprovided by VGNC
Official Full Name
epidermal growth factor receptorprovided by VGNC
Primary source
VGNC:VGNC:81309
See related
Ensembl:ENSMMUG00000022394
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See EGFR in Genome Data Viewer
Location:
chromosome: 3
Exon count:
30
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (60060391..60254099, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (54322618..54515307)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676912 Neighboring gene uncharacterized LOC114676913 Neighboring gene caltractin ICL1a-like Neighboring gene ATP synthase subunit beta, mitochondrial Neighboring gene rho GTPase-activating protein 5 pseudogene

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables epidermal growth factor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables epidermal growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
epidermal growth factor receptor
Names
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
XP_014988922.2
XP_014988923.2
XP_028701599.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    60060391..60254099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015133436.2XP_014988922.2  epidermal growth factor receptor isoform X1

    UniProtKB/Swiss-Prot
    F6YXS7, G7ML99, H9FAB2, P55245
    UniProtKB/TrEMBL
    A0A1D5QDK1
    Related
    ENSMMUP00000046120.2, ENSMMUT00000071491.2
    Conserved Domains (5) summary
    cd12093
    Location:634677
    TM_ErbB1; Transmembrane domain of Epidermal Growth Factor Receptor or ErbB1, a Protein Tyrosine Kinase
    cd05108
    Location:7041016
    PTKc_EGFR; Catalytic domain of the Protein Tyrosine Kinase, Epidermal Growth Factor Receptor
    pfam00757
    Location:185335
    Furin-like; Furin-like cysteine rich region
    pfam14843
    Location:505637
    GF_recep_IV; Growth factor receptor domain IV
    pfam01030
    Location:57166
    Recep_L_domain; Receptor L domain
  2. XM_015133437.2XP_014988923.2  epidermal growth factor receptor isoform X2

    UniProtKB/TrEMBL
    A0A1D5RE09
    Related
    ENSMMUP00000058552.2, ENSMMUT00000062209.2
    Conserved Domains (5) summary
    cd12093
    Location:581624
    TM_ErbB1; Transmembrane domain of Epidermal Growth Factor Receptor or ErbB1, a Protein Tyrosine Kinase
    cd05108
    Location:651963
    PTKc_EGFR; Catalytic domain of the Protein Tyrosine Kinase, Epidermal Growth Factor Receptor
    pfam00757
    Location:132282
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:4115
    Recep_L_domain; Receptor L domain
    pfam14843
    Location:452584
    GF_recep_IV; Growth factor receptor domain IV
  3. XM_028845766.1XP_028701599.1  epidermal growth factor receptor isoform X3

    Conserved Domains (5) summary
    cd12093
    Location:367410
    TM_ErbB1; Transmembrane domain of Epidermal Growth Factor Receptor or ErbB1, a Protein Tyrosine Kinase
    cd05108
    Location:437749
    PTKc_EGFR; Catalytic domain of the Protein Tyrosine Kinase, Epidermal Growth Factor Receptor
    pfam00757
    Location:1468
    Furin-like; Furin-like cysteine rich region
    pfam14843
    Location:238370
    GF_recep_IV; Growth factor receptor domain IV
    pfam01030
    Location:94212
    Recep_L_domain; Receptor L domain