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trmt2b tRNA methyltransferase 2 homolog B [ Danio rerio (zebrafish) ]

Gene ID: 606657, updated on 9-Dec-2024

Summary

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Official Symbol
trmt2bprovided by ZNC
Official Full Name
tRNA methyltransferase 2 homolog Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050809-101
See related
Ensembl:ENSDARG00000033967 AllianceGenome:ZFIN:ZDB-GENE-050809-101
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7160396; wu:fc49d02; zgc:162982
Summary
Predicted to enable rRNA (uridine-C5-)-methyltransferase activity and tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent. Predicted to act upstream of or within methylation; rRNA processing; and tRNA processing. Predicted to be active in mitochondrion. Orthologous to human TRMT2B (tRNA methyltransferase 2 homolog B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See trmt2b in Genome Data Viewer
Location:
chromosome: 13
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (30033036..30034787, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (29902586..29904304, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene wingless-type MMTV integration site family, member 8b Neighboring gene stearoyl-CoA desaturase b Neighboring gene DnaJ heat shock protein family (Hsp40) member B12a Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 Neighboring gene trypsin like peroxisomal matrix peptidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (uridine-C5-)-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent IEA
Inferred from Electronic Annotation
more info
  
enables tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
tRNA (uracil-5-)-methyltransferase homolog B
Names
DKEYP-115D2.4
TRM2 homolog B
TRM2 tRNA methyltransferase 2 homolog B
rRNA (uracil-5-)-methyltransferase TRMT2B
tRNA (uracil(54)-C(5))-methyltransferase homolog-B
tRNA (uracil-5-)-methyltransferase homolog
tRNA (uracil-5-)-methyltransferase homolog-B
NP_001116415.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122943.2 → NP_001116415.2  tRNA (uracil-5-)-methyltransferase homolog B

    Status: VALIDATED

    Source sequence(s)
    AL929344
    UniProtKB/Swiss-Prot
    A4QP75, B7ZD53
    UniProtKB/TrEMBL
    A0A0R4I9B6
    Related
    ENSDARP00000112957.1, ENSDART00000143745.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    30033036..30034787 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4QP75.2 GenPept UniProtKB/Swiss-Prot:A4QP75

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