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PLEKHA1 pleckstrin homology domain containing A1 [ Homo sapiens (human) ]

Gene ID: 59338, updated on 27-Nov-2024

Summary

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Official Symbol
PLEKHA1provided by HGNC
Official Full Name
pleckstrin homology domain containing A1provided by HGNC
Primary source
HGNC:HGNC:14335
See related
Ensembl:ENSG00000107679 MIM:607772; AllianceGenome:HGNC:14335
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TAPP1
Summary
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]
Expression
Ubiquitous expression in skin (RPKM 23.3), lung (RPKM 17.3) and 24 other tissues See more
Orthologs
mouse all
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Genomic context

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See PLEKHA1 in Genome Data Viewer
Location:
10q26.13
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (122374708..122442600)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (123270978..123338841)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (124134224..124202116)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:124050601-124051101 Neighboring gene BTB domain containing 16 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:124053014-124054004 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4142 Neighboring gene RNA, U6 small nuclear 728, pseudogene Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:124128134-124128658 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2889 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2890 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2892 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2893 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2891 Neighboring gene microRNA 3941 Neighboring gene HTRA1 and ARMS2 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:124233495-124234018 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:124234019-124234540 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:124235637-124236362 Neighboring gene age-related maculopathy susceptibility 2 Neighboring gene HtrA serine peptidase 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:124253973-124255172 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:124264199-124264698

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity. Thomas CC, et al. Biochem J, 2001 Sep 1. PMID 11513726, Free PMC Article
  2. Susceptibility genes for age-related maculopathy on chromosome 10q26. Jakobsdottir J, et al. Am J Hum Genet, 2005 Sep. PMID 16080115, Free PMC Article
  3. Polymorphisms in Selected Genes and Their Association with Age-Related Macular Degeneration in a Chinese Population. Huang Q, et al. Med Sci Monit, 2018 Mar 22. PMID 29565837, Free PMC Article
  4. Gene Structure of the 10q26 Locus: A Clue to Cracking the ARMS2/HTRA1 Riddle? Kortvely E, et al. Adv Exp Med Biol, 2016. PMID 26427389
  5. Cumulative association between age-related macular degeneration and less studied genetic variants in PLEKHA1/ARMS2/HTRA1: a meta and gene-cluster analysis. Yu W, et al. Mol Biol Rep, 2013 Oct. PMID 24013816, Free PMC Article

See all (63) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. investigated the association of PLEKHA1 958A/G, polymorphisms with Age-Related Macular Degeneration (AMD) risk. PLEKHA1 958A/G polymorphism was associated with a decreased AMD risk (additive model: aOR=0.722, 95% CI=0.450-0.979, P=0.019; allele model: aOR=0.883, 95% CI=0.736-0.992, P=0.014)
    Title: Polymorphisms in Selected Genes and Their Association with Age-Related Macular Degeneration in a Chinese Population.
  2. Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1, ARMS2, and HTRA1 with high linkage disequilibrium.
    Title: Gene Structure of the 10q26 Locus: A Clue to Cracking the ARMS2/HTRA1 Riddle?
  3. CX3CR1 (T280M and V249I) and PLEKHA1 (A320T) polymorphisms were not found to be associated with age-related macular degeneration in an Indian population.
    Title: Study of Polymorphisms in CX3CR1, PLEKHA1 and VEGF genes as risk factors for age-related macular degeneration in Indian patients.
  4. This study provides evidence of the joint contribution of genetic variants in PLEKHA1/ARMS2/HTRA1 to age-related macular degeneration risk.
    Title: Cumulative association between age-related macular degeneration and less studied genetic variants in PLEKHA1/ARMS2/HTRA1: a meta and gene-cluster analysis.
  5. Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator)
    Title: Integrative predictive model of coronary artery calcification in atherosclerosis.
  6. Independent of CFH genotype or smoking history, an individual's risk of AMD (age-related macular degeneration) could be increased or decreased, depending on their genotype or haplotype in the 10q26 region.
    Title: Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.
  7. Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
    Title: Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.
  8. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
    Title: PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population.
  9. Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
    Title: CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses.
  10. Observational study of gene-disease association. (HuGE Navigator)
    Title: A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.
Submit: New GeneRIF Correction See all GeneRIFs (14)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
EBI GWAS Catalog
Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.
EBI GWAS Catalog
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables PDZ domain binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables phosphatidylinositol-3,4-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-3,4-bisphosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in Leydig cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in androgen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to hydrogen peroxide IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in establishment of protein localization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in estrogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in face morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in luteinization IEA
Inferred from Electronic Annotation
more info
  
involved_in multicellular organism growth IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in platelet-derived growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in post-embryonic development IEA
Inferred from Electronic Annotation
more info
  
involved_in roof of mouth development IEA
Inferred from Electronic Annotation
more info
  
involved_in ruffle organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in skeletal system morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in extracellular exosome HDA PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in ruffle membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family A member 1
Names
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
tandem PH domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027823.2 RefSeqGene

    Range
    5002..62639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001001974.4 → NP_001001974.1  pleckstrin homology domain-containing family A member 1 isoform 1

    See identical proteins and their annotated locations for NP_001001974.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 5-9 all encode the same isoform (1).
    Source sequence(s)
    AL133603, BC001136, BC042458
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Related
    ENSP00000357986.3, ENST00000368990.8
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  2. NM_001195608.2 → NP_001182537.1  pleckstrin homology domain-containing family A member 1 isoform 2

    See identical proteins and their annotated locations for NP_001182537.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) is shorter at the 5' UTR and includes an alternate exon, which results in a frameshift, compared to variant 1. The resulting isoform (2) has a distinct C-terminus, compared to isoform 1. Variants 3, 10, and 11 all encode the same isoform (2).
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS55730.1
    UniProtKB/Swiss-Prot
    Q9HB21
    UniProtKB/TrEMBL
    B3KQL5
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  3. NM_001330178.2 → NP_001317107.1  pleckstrin homology domain-containing family A member 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate exon in the 3' coding region, which results in a frameshift compared to variant 1. The resulting isoform (3) is shorter than and has a distinct C-terminus compared to isoform 1. Variants 4 and 12-16 all encode the same isoform (3).
    Source sequence(s)
    AK075159, BC042458, BG248876, BX842242, CN310745, CN310748, DN989473, R26739
    Consensus CDS
    CCDS81517.1
    UniProtKB/TrEMBL
    Q5RGS4
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  4. NM_001377230.1 → NP_001364159.1  pleckstrin homology domain-containing family A member 1 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variants 1, 2, and 6-9, encodes isoform 1.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  5. NM_001377231.1 → NP_001364160.1  pleckstrin homology domain-containing family A member 1 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variants 1, 2, 5, and 7-9, encodes isoform 1.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  6. NM_001377232.1 → NP_001364161.1  pleckstrin homology domain-containing family A member 1 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variants 1, 2, 5, 6, 8, and 9, encodes isoform 1.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  7. NM_001377234.1 → NP_001364163.1  pleckstrin homology domain-containing family A member 1 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variants 1, 2, 5-7, and 9, encodes isoform 1.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  8. NM_001377235.1 → NP_001364164.1  pleckstrin homology domain-containing family A member 1 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 1, 2, and 5-8, encodes isoform 1.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  9. NM_001377237.1 → NP_001364166.1  pleckstrin homology domain-containing family A member 1 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 3 and 11, encodes isoform 2.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS55730.1
    Related
    ENSP00000357984.2, ENST00000368988.5
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  10. NM_001377238.1 → NP_001364167.1  pleckstrin homology domain-containing family A member 1 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 3 and 10, encodes isoform 2.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS55730.1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  11. NM_001377240.1 → NP_001364169.1  pleckstrin homology domain-containing family A member 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 4 and 13-16, encodes isoform 3.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS81517.1
    UniProtKB/TrEMBL
    Q5RGS4
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  12. NM_001377241.1 → NP_001364170.1  pleckstrin homology domain-containing family A member 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 4, 12, and 14-16, encodes isoform 3.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS81517.1
    UniProtKB/TrEMBL
    Q5RGS4
    Related
    ENSP00000357985.1, ENST00000368989.6
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  13. NM_001377242.1 → NP_001364171.1  pleckstrin homology domain-containing family A member 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 4, 12, 13, 15, and 16, encodes isoform 3.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS81517.1
    UniProtKB/TrEMBL
    Q5RGS4
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  14. NM_001377243.1 → NP_001364172.1  pleckstrin homology domain-containing family A member 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 4, 12-14, and 16, encodes isoform 3.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS81517.1
    UniProtKB/TrEMBL
    Q5RGS4
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  15. NM_001377244.1 → NP_001364173.1  pleckstrin homology domain-containing family A member 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 4 and 12-15, encodes isoform 3.
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS81517.1
    UniProtKB/TrEMBL
    Q5RGS4
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  16. NM_001377245.1 → NP_001364174.1  pleckstrin homology domain-containing family A member 1 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variant 18, encodes isoform 4.
    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  17. NM_001377246.1 → NP_001364175.1  pleckstrin homology domain-containing family A member 1 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variant 17, encodes isoform 4.
    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  18. NM_001377247.1 → NP_001364176.1  pleckstrin homology domain-containing family A member 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13271
    Location:174 → 287
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 110
    PH-like; Pleckstrin homology-like domain

  19. NM_001377248.1 → NP_001364177.1  pleckstrin homology domain-containing family A member 1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  20. NM_001377249.1 → NP_001364178.1  pleckstrin homology domain-containing family A member 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13271
    Location:165 → 278
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:48 → 97
    PH-like; Pleckstrin homology-like domain

  21. NM_001377250.1 → NP_001364179.1  pleckstrin homology domain-containing family A member 1 isoform 8

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13271
    Location:182 → 295
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 114
    PH-like; Pleckstrin homology-like domain

  22. NM_001377251.1 → NP_001364180.1  pleckstrin homology domain-containing family A member 1 isoform 9

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13271
    Location:174 → 287
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 110
    PH-like; Pleckstrin homology-like domain

  23. NM_001377252.1 → NP_001364181.1  pleckstrin homology domain-containing family A member 1 isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variants 25 and 26, encodes isoform 10.
    Source sequence(s)
    BX664700, BX842242
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13271
    Location:137 → 250
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 75
    PH-like; Pleckstrin homology-like domain

  24. NM_001377253.1 → NP_001364182.1  pleckstrin homology domain-containing family A member 1 isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variants 24 and 26, encodes isoform 10.
    Source sequence(s)
    BX664700, BX842242
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13271
    Location:137 → 250
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 75
    PH-like; Pleckstrin homology-like domain

  25. NM_001377254.1 → NP_001364183.1  pleckstrin homology domain-containing family A member 1 isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 24 and 25, encodes isoform 10.
    Source sequence(s)
    BX664700, BX842242
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13271
    Location:137 → 250
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 75
    PH-like; Pleckstrin homology-like domain

  26. NM_001377255.1 → NP_001364184.1  pleckstrin homology domain-containing family A member 1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13271
    Location:137 → 250
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 75
    PH-like; Pleckstrin homology-like domain

  27. NM_001377256.1 → NP_001364185.1  pleckstrin homology domain-containing family A member 1 isoform 12

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13271
    Location:143 → 256
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 75
    PH-like; Pleckstrin homology-like domain

  28. NM_001377257.1 → NP_001364186.1  pleckstrin homology domain-containing family A member 1 isoform 13

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (2) summary
    cd13271
    Location:137 → 250
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat
    cl17171
    Location:1 → 75
    PH-like; Pleckstrin homology-like domain

  29. NM_001377258.1 → NP_001364187.1  pleckstrin homology domain-containing family A member 1 isoform 14

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242
    Conserved Domains (1) summary
    cl17171
    Location:1 → 117
    PH-like; Pleckstrin homology-like domain

  30. NM_021622.5 → NP_067635.2  pleckstrin homology domain-containing family A member 1 isoform 1

    See identical proteins and their annotated locations for NP_067635.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1, 2, and 5-9 all encode the same isoform (1).
    Source sequence(s)
    BX664700, BX842242
    Consensus CDS
    CCDS7629.1
    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

RNA

  1. NR_165160.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242

  2. NR_165161.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242

  3. NR_165162.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242

  4. NR_165164.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242

  5. NR_165165.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    BX664700, BX842242

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    122374708..122442600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448108.2 → XP_024303876.1  pleckstrin homology domain-containing family A member 1 isoform X1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  2. XM_047425608.1 → XP_047281564.1  pleckstrin homology domain-containing family A member 1 isoform X4

  3. XM_024448114.2 → XP_024303882.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  4. XM_017016478.3 → XP_016871967.1  pleckstrin homology domain-containing family A member 1 isoform X1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  5. XM_017016479.3 → XP_016871968.1  pleckstrin homology domain-containing family A member 1 isoform X2

  6. XM_024448109.2 → XP_024303877.1  pleckstrin homology domain-containing family A member 1 isoform X1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  7. XM_047425609.1 → XP_047281565.1  pleckstrin homology domain-containing family A member 1 isoform X4

  8. XM_011540021.2 → XP_011538323.1  pleckstrin homology domain-containing family A member 1 isoform X1

    See identical proteins and their annotated locations for XP_011538323.1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  9. XM_011540018.2 → XP_011538320.1  pleckstrin homology domain-containing family A member 1 isoform X1

    See identical proteins and their annotated locations for XP_011538320.1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  10. XM_017016483.2 → XP_016871972.1  pleckstrin homology domain-containing family A member 1 isoform X4

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  11. XM_017016487.2 → XP_016871976.1  pleckstrin homology domain-containing family A member 1 isoform X5

    UniProtKB/TrEMBL
    Q5RGS4
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  12. XM_024448110.2 → XP_024303878.1  pleckstrin homology domain-containing family A member 1 isoform X1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  13. XM_047425612.1 → XP_047281568.1  pleckstrin homology domain-containing family A member 1 isoform X5

    UniProtKB/TrEMBL
    Q5RGS4

  14. XM_047425599.1 → XP_047281555.1  pleckstrin homology domain-containing family A member 1 isoform X1

  15. XM_047425611.1 → XP_047281567.1  pleckstrin homology domain-containing family A member 1 isoform X4

  16. XM_047425613.1 → XP_047281569.1  pleckstrin homology domain-containing family A member 1 isoform X5

    UniProtKB/TrEMBL
    Q5RGS4

  17. XM_047425606.1 → XP_047281562.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21

  18. XM_011540017.2 → XP_011538319.1  pleckstrin homology domain-containing family A member 1 isoform X1

    See identical proteins and their annotated locations for XP_011538319.1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  19. XM_017016484.2 → XP_016871973.1  pleckstrin homology domain-containing family A member 1 isoform X4

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  20. XM_011540022.2 → XP_011538324.1  pleckstrin homology domain-containing family A member 1 isoform X1

    See identical proteins and their annotated locations for XP_011538324.1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  21. XM_047425610.1 → XP_047281566.1  pleckstrin homology domain-containing family A member 1 isoform X4

  22. XM_017016482.2 → XP_016871971.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  23. XM_047425598.1 → XP_047281554.1  pleckstrin homology domain-containing family A member 1 isoform X1

  24. XM_047425605.1 → XP_047281561.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21

  25. XM_011540019.2 → XP_011538321.1  pleckstrin homology domain-containing family A member 1 isoform X1

    See identical proteins and their annotated locations for XP_011538321.1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  26. XM_011540024.2 → XP_011538326.1  pleckstrin homology domain-containing family A member 1 isoform X1

    See identical proteins and their annotated locations for XP_011538326.1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  27. XM_047425603.1 → XP_047281559.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21

  28. XM_047425600.1 → XP_047281556.1  pleckstrin homology domain-containing family A member 1 isoform X1

  29. XM_024448113.2 → XP_024303881.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21
    UniProtKB/TrEMBL
    B2RBH1
    Related
    ENSP00000376547.3, ENST00000392799.7
    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  30. XM_024448107.2 → XP_024303875.1  pleckstrin homology domain-containing family A member 1 isoform X1

    Conserved Domains (2) summary
    cd13270
    Location:1 → 117
    PH1_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, N-terminal repeat
    cd13271
    Location:185 → 298
    PH2_TAPP1_2; Tandem PH-domain-containing proteins 1 and 2 Pleckstrin homology (PH) domain, C-terminal repeat

  31. XM_047425607.1 → XP_047281563.1  pleckstrin homology domain-containing family A member 1 isoform X4

  32. XM_047425602.1 → XP_047281558.1  pleckstrin homology domain-containing family A member 1 isoform X1

  33. XM_047425604.1 → XP_047281560.1  pleckstrin homology domain-containing family A member 1 isoform X3

    UniProtKB/Swiss-Prot
    B3KQ55, D3DRE2, Q9BVK0, Q9HB21

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    123270978..123338841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054366487.1 → XP_054222462.1  pleckstrin homology domain-containing family A member 1 isoform X1

  2. XM_054366506.1 → XP_054222481.1  pleckstrin homology domain-containing family A member 1 isoform X4

  3. XM_054366501.1 → XP_054222476.1  pleckstrin homology domain-containing family A member 1 isoform X3

  4. XM_054366480.1 → XP_054222455.1  pleckstrin homology domain-containing family A member 1 isoform X1

  5. XM_054366495.1 → XP_054222470.1  pleckstrin homology domain-containing family A member 1 isoform X2

  6. XM_054366484.1 → XP_054222459.1  pleckstrin homology domain-containing family A member 1 isoform X1

  7. XM_054366507.1 → XP_054222482.1  pleckstrin homology domain-containing family A member 1 isoform X4

  8. XM_054366483.1 → XP_054222458.1  pleckstrin homology domain-containing family A member 1 isoform X1

  9. XM_054366481.1 → XP_054222456.1  pleckstrin homology domain-containing family A member 1 isoform X1

  10. XM_054366504.1 → XP_054222479.1  pleckstrin homology domain-containing family A member 1 isoform X4

  11. XM_054366510.1 → XP_054222485.1  pleckstrin homology domain-containing family A member 1 isoform X5

    UniProtKB/TrEMBL
    Q5RGS4

  12. XM_054366489.1 → XP_054222464.1  pleckstrin homology domain-containing family A member 1 isoform X1

  13. XM_054366511.1 → XP_054222486.1  pleckstrin homology domain-containing family A member 1 isoform X5

    UniProtKB/TrEMBL
    Q5RGS4

  14. XM_054366486.1 → XP_054222461.1  pleckstrin homology domain-containing family A member 1 isoform X1

  15. XM_054366509.1 → XP_054222484.1  pleckstrin homology domain-containing family A member 1 isoform X4

  16. XM_054366512.1 → XP_054222487.1  pleckstrin homology domain-containing family A member 1 isoform X5

    UniProtKB/TrEMBL
    Q5RGS4

  17. XM_054366502.1 → XP_054222477.1  pleckstrin homology domain-containing family A member 1 isoform X3

  18. XM_054366482.1 → XP_054222457.1  pleckstrin homology domain-containing family A member 1 isoform X1

  19. XM_054366503.1 → XP_054222478.1  pleckstrin homology domain-containing family A member 1 isoform X4

  20. XM_054366491.1 → XP_054222466.1  pleckstrin homology domain-containing family A member 1 isoform X1

  21. XM_054366508.1 → XP_054222483.1  pleckstrin homology domain-containing family A member 1 isoform X4

  22. XM_054366498.1 → XP_054222473.1  pleckstrin homology domain-containing family A member 1 isoform X3

  23. XM_054366485.1 → XP_054222460.1  pleckstrin homology domain-containing family A member 1 isoform X1

  24. XM_054366500.1 → XP_054222475.1  pleckstrin homology domain-containing family A member 1 isoform X3

  25. XM_054366488.1 → XP_054222463.1  pleckstrin homology domain-containing family A member 1 isoform X1

  26. XM_054366490.1 → XP_054222465.1  pleckstrin homology domain-containing family A member 1 isoform X1

  27. XM_054366496.1 → XP_054222471.1  pleckstrin homology domain-containing family A member 1 isoform X3

  28. XM_054366493.1 → XP_054222468.1  pleckstrin homology domain-containing family A member 1 isoform X1

  29. XM_054366497.1 → XP_054222472.1  pleckstrin homology domain-containing family A member 1 isoform X3

  30. XM_054366492.1 → XP_054222467.1  pleckstrin homology domain-containing family A member 1 isoform X1

  31. XM_054366505.1 → XP_054222480.1  pleckstrin homology domain-containing family A member 1 isoform X4

  32. XM_054366494.1 → XP_054222469.1  pleckstrin homology domain-containing family A member 1 isoform X1

  33. XM_054366499.1 → XP_054222474.1  pleckstrin homology domain-containing family A member 1 isoform X3

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HB21.2 GenPept UniProtKB/Swiss-Prot:Q9HB21

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